Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1209103 | 0.91 | ALDH1A1 (0.42) | MAPTTP53L3MBTL1MEN1KMT2A | |
| SCHEMBL14293203 | 0.88 | ALDH1A1 (0.39) | THRBMAPTLMNATP53L3MBTL1 | |
| SCHEMBL12895475 | 0.87 | THRB (0.34) | THRBMAPTLMNATP53L3MBTL1 | |
| SCHEMBL12895485 | 0.86 | THRB (0.35) | THRBMAPTLMNATP53L3MBTL1 | |
| SCHEMBL12895479 | 0.86 | THRB (0.34) | THRBMAPTLMNATP53L3MBTL1 | |
| SCHEMBL12895478 | 0.85 | THRB (0.34) | THRBMAPTLMNAL3MBTL1MEN1 | |
| SCHEMBL12895691 | 0.85 | SLC8A1 (0.35) | THRBMAPTLMNATP53L3MBTL1 | |
| SCHEMBL12895476 | 0.85 | KMT2A (0.35) | THRBMAPTLMNATP53MEN1 | |
| SCHEMBL12895367 | 0.82 | ALDH1A1 (0.38) | THRBMAPTTP53L3MBTL1MEN1 | |
| SCHEMBL12894588 | 0.82 | THRB (0.41) | THRBMAPTLMNATP53L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008020045-A1 | TETRAHYDROBENZOTHIOPHENE DERIVATIVES | 4SC AG (DE) | 2008-02-21 | — | — | WO | disclosed |