Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12895371 | 0.93 | KDM4E (0.35) | RAB9AMAPTCYP3A4ALDH1A1 | |
| SCHEMBL12895374 | 0.91 | THRB (0.35) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL1208832 | 0.90 | ALDH1A1 (0.43) | MEN1KMT2AHPGDRAB9AMAPT | |
| SCHEMBL14293242 | 0.89 | MEN1 (0.36) | MEN1KMT2ATSHRHPGDRAB9A | |
| SCHEMBL14293234 | 0.87 | HPGD (0.36) | MEN1KMT2ATSHRHPGDRAB9A | |
| SCHEMBL14293236 | 0.87 | ALDH1A1 (0.30) | ALDH1A1HTT | |
| SCHEMBL12895260 | 0.86 | MEN1 (0.35) | MEN1KMT2ATSHRHPGDRAB9A | |
| SCHEMBL14293206 | 0.86 | ALDH1A1 (0.37) | MEN1KMT2ATSHRHPGDRAB9A | |
| SCHEMBL14293232 | 0.84 | MEN1 (0.36) | MEN1KMT2ATSHRHPGDRAB9A | |
| SCHEMBL14292397 | 0.84 | HPGD (0.37) | MEN1KMT2ATSHRHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008020045-A1 | TETRAHYDROBENZOTHIOPHENE DERIVATIVES | 4SC AG (DE) | 2008-02-21 | — | — | WO | disclosed |