Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4314370 | 0.85 | THRB (0.42) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL27701673 | 0.77 | THRB (0.47) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL6757327 | 0.77 | TSHR (0.59) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL14293579 | 0.77 | THRB (0.50) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL3802304 | 0.77 | THRB (0.55) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL4313868 | 0.77 | THRB (0.55) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL11023086 | 0.75 | THRB (0.48) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL234178 | 0.75 | TSHR (0.47) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL8473833 | 0.74 | THRB (0.52) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL29025167 | 0.74 | TSHR (0.43) | THRBTSHRALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008019111-A2 | TELOMER COMPOSITIONS AND PRODUCTION PROCESSES | GREAT LAKES CHEMICAL CORPORATION (US) | 2008-02-14 | — | — | WO | disclosed |