Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3802304 | 0.96 | THRB (0.55) | THRBTSHRALDH1A1TDP1POLB | |
| SCHEMBL11584823 | 0.94 | TSHR (0.53) | THRBTSHRALDH1A1TDP1POLB | |
| SCHEMBL11528248 | 0.91 | TSHR (0.59) | THRBTSHRALDH1A1TDP1CYP3A4 | |
| SCHEMBL11528645 | 0.90 | TSHR (0.62) | THRBTSHRALDH1A1TDP1POLB | |
| SCHEMBL20148192 | 0.88 | TSHR (0.65) | THRBTSHRALDH1A1TDP1POLB | |
| SCHEMBL19294374 | 0.86 | THRB (0.46) | THRBTSHRALDH1A1TDP1POLB | |
| SCHEMBL18953068 | 0.85 | TSHR (0.59) | THRBTSHRALDH1A1TDP1POLB | |
| SCHEMBL6757327 | 0.84 | TSHR (0.59) | THRBTSHRALDH1A1TDP1POLB | |
| SCHEMBL2817127 | 0.84 | TSHR (0.64) | THRBTSHRALDH1A1TDP1POLB | |
| SCHEMBL11532047 | 0.84 | TSHR (0.59) | THRBTSHRALDH1A1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009132206-A1 | COMPOSITIONS AND METHODS FOR INTRACELLULAR DELIVERY AND RELEASE OF CARGO | LIQUIDIA TECHNOLOGIES, INC. (US) | 2009-10-29 | — | — | WO | disclosed |