Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | IDH2 | P48735 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | BCL6 | P41182 | 2/20 | 0.42 |
| ▸ | INSR | P06213 | 1/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | CTSV | O60911 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | CTSH | P09668 | 1/20 | 0.40 |
| ▸ | CASP14 | P31944 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4838910 | 0.90 | RAB9A (0.53) | RAB9AIDH2HTTMEN1MAPT | |
| SCHEMBL14294123 | 0.89 | IDH2 (0.46) | RAB9AIDH2HTTMEN1MAPT | |
| SCHEMBL4832415 | 0.88 | BCL6 (0.56) | RAB9AIDH2HTTMEN1MAPT | |
| SCHEMBL14293975 | 0.87 | RAB9A (0.45) | RAB9AIDH2HTTMEN1MAPT | |
| SCHEMBL14302330 | 0.84 | MAPT (0.59) | RAB9AHTTMEN1MAPTKMT2A | |
| SCHEMBL4838490 | 0.82 | IDH2 (0.46) | RAB9AIDH2HTTMEN1MAPT | |
| SCHEMBL14294052 | 0.81 | SMN1; SMN2 (0.47) | RAB9AIDH2HTTMEN1MAPT | |
| SCHEMBL14302184 | 0.81 | RAB9A (0.59) | RAB9AHTTMEN1MAPTKMT2A | |
| SCHEMBL4832649 | 0.80 | BCL6 (0.49) | RAB9AIDH2HTTMEN1MAPT | |
| SCHEMBL4832885 | 0.80 | RAB9A (0.65) | RAB9AS1PR1CTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7332489-B2 | Methods and compositions of novel triazine compounds | REDDY US THERAPEUTICS, INC. (US) | 2008-02-19 | — | — | US | disclosed |