Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH2 | P48735 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 3/20 | 0.41 |
| ▸ | BCL6 | P41182 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | RPS6KA6 | Q9UK32 | 1/20 | 0.39 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.39 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14293971 | 0.91 | RPS6KA6 (0.41) | IDH2EGFRRPS6KA6 | |
| SCHEMBL4837042 | 0.90 | IDH2 (0.55) | IDH2MEN1MAPTHTTKMT2A | |
| SCHEMBL14293973 | 0.89 | RAB9A (0.46) | IDH2MEN1MAPTHTTKMT2A | |
| SCHEMBL4832649 | 0.88 | BCL6 (0.49) | IDH2MEN1MAPTHTTKMT2A | |
| SCHEMBL14293970 | 0.87 | CTSS (0.44) | IDH2MEN1MAPTHTTKMT2A | |
| SCHEMBL14293851 | 0.85 | EHMT2 (0.39) | HTTSMN1; SMN2NPSR1EHMT2EHMT1 | |
| SCHEMBL4838593 | 0.82 | IDH2 (0.48) | IDH2MEN1MAPTHTTKMT2A | |
| SCHEMBL14293968 | 0.82 | AXL (0.37) | IDH2EGFRRPS6KA6EHMT2EHMT1 | |
| SCHEMBL14302199 | 0.81 | NPSR1 (0.53) | MEN1MAPTHTTKMT2ASMN1; SMN2 | |
| SCHEMBL14294052 | 0.81 | SMN1; SMN2 (0.47) | IDH2MEN1MAPTHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7332489-B2 | Methods and compositions of novel triazine compounds | REDDY US THERAPEUTICS, INC. (US) | 2008-02-19 | — | — | US | disclosed |