Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 4/20 | 0.40 |
| ▸ | CTSK | P43235 | 4/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | RPS6KA6 | Q9UK32 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | CTSV | O60911 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSH | P09668 | 1/20 | 0.39 |
| ▸ | CASP14 | P31944 | 1/20 | 0.39 |
| ▸ | CASP4 | P49662 | 1/20 | 0.39 |
| ▸ | CASP5 | P51878 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | CTSZ | Q9UBR2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4832874 | 0.87 | GALR1 (0.47) | RAB9ACTSSCTSKROCK1CTSL | |
| SCHEMBL14294400 | 0.87 | ROCK1 (0.52) | RAB9ACTSSCTSKROCK1S1PR1 | |
| SCHEMBL4829661 | 0.86 | RAB9A (0.46) | RAB9ACTSSCTSKS1PR1RPS6KA6 | |
| SCHEMBL14293957 | 0.82 | RAB9A (0.43) | RAB9ACTSSCTSKS1PR1RPS6KA6 | |
| SCHEMBL14293956 | 0.81 | RAB9A (0.53) | RAB9ACTSSCTSKS1PR1RPS6KA6 | |
| SCHEMBL5030715 | 0.80 | CTSS (0.42) | RAB9ACTSSCTSKROCK1S1PR1 | |
| SCHEMBL14293974 | 0.80 | RAB9A (0.41) | RAB9ACTSSCTSKS1PR1RPS6KA6 | |
| SCHEMBL14294404 | 0.80 | RAB9A (0.41) | RAB9ACTSSCTSKS1PR1RPS6KA6 | |
| SCHEMBL14294101 | 0.79 | RAB9A (0.41) | RAB9ACTSSCTSKS1PR1RPS6KA6 | |
| SCHEMBL14294098 | 0.79 | IDH2 (0.43) | RAB9ACTSSCTSKS1PR1RPS6KA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7335656-B2 | Stent with a disposed traiazine compound such as 6-(3-Chloro-4-methoxy-phenoxy)-N-cycloheptyl-N'-methyl-N'-(1-methyl-piperidin-4-yl)-[1,3,5]triazine-2,4-diamine for inhibiting smooth muscle proliferation; restenosis and atherosclerosis | REDDY US THERAPEUTICS, INC. (US) | 2008-02-26 | — | — | US | disclosed |
| US-7332489-B2 | Methods and compositions of novel triazine compounds | REDDY US THERAPEUTICS, INC. (US) | 2008-02-19 | — | — | US | disclosed |