Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 8/20 | 0.47 |
| ▸ | EHMT1 | Q9H9B1 | 7/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | CRHBP | P24387 | 2/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | INSR | P06213 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14294097 | 0.92 | EHMT2 (0.49) | EHMT2EHMT1CRHBPCRHR2APP | |
| SCHEMBL5032253 | 0.91 | EHMT2 (0.47) | EHMT2EHMT1ALOX15CRHBPCRHR2 | |
| SCHEMBL5030894 | 0.91 | EHMT2 (0.47) | EHMT2EHMT1ALOX15CRHBPCRHR2 | |
| SCHEMBL14533522 | 0.90 | EHMT2 (0.46) | EHMT2EHMT1ALOX15CRHBPCRHR2 | |
| SCHEMBL14268325 | 0.84 | EHMT2 (0.51) | EHMT2EHMT1NPSR1CTSSCTSK | |
| SCHEMBL4828965 | 0.83 | EHMT2 (0.49) | EHMT2EHMT1LMNAAPPBCHE | |
| SCHEMBL4838191 | 0.83 | EHMT2 (0.49) | EHMT2EHMT1APPBCHEACHE | |
| SCHEMBL14533520 | 0.82 | EHMT2 (0.47) | EHMT2EHMT1APPBCHEACHE | |
| SCHEMBL6916172 | 0.79 | LMNA (0.43) | EHMT2EHMT1ALOX15CRHBPCRHR2 | |
| SCHEMBL5552484 | 0.78 | EHMT2 (0.47) | EHMT2EHMT1ALOX15CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7335656-B2 | Stent with a disposed traiazine compound such as 6-(3-Chloro-4-methoxy-phenoxy)-N-cycloheptyl-N'-methyl-N'-(1-methyl-piperidin-4-yl)-[1,3,5]triazine-2,4-diamine for inhibiting smooth muscle proliferation; restenosis and atherosclerosis | REDDY US THERAPEUTICS, INC. (US) | 2008-02-26 | — | — | US | disclosed |
| US-7332489-B2 | Methods and compositions of novel triazine compounds | REDDY US THERAPEUTICS, INC. (US) | 2008-02-19 | — | — | US | disclosed |