Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | EHMT2 | Q96KQ7 | 4/20 | 0.39 |
| ▸ | EHMT1 | Q9H9B1 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5552484 | 0.87 | EHMT2 (0.47) | LMNATSHRALOX15NPSR1POLB | |
| SCHEMBL5030894 | 0.86 | EHMT2 (0.47) | LMNATSHRALOX15NPSR1POLB | |
| SCHEMBL4839029 | 0.83 | GALR1 (0.46) | EHMT2EHMT1FGFR3 | |
| SCHEMBL14294397 | 0.79 | EHMT2 (0.47) | LMNATSHRALOX15NPSR1POLB | |
| SCHEMBL4828965 | 0.78 | EHMT2 (0.49) | LMNAEHMT2EHMT1MAPT | |
| SCHEMBL4832446 | 0.78 | GALR1 (0.42) | LMNANPSR1EHMT2EHMT1MAPT | |
| SCHEMBL5032253 | 0.76 | EHMT2 (0.47) | LMNATSHRALOX15NPSR1POLB | |
| SCHEMBL14533522 | 0.75 | EHMT2 (0.46) | LMNATSHRALOX15NPSR1POLB | |
| SCHEMBL6237774 | 0.74 | EHMT2 (0.45) | TSHRSLC2A1EHMT2EHMT1 | |
| SCHEMBL6270071 | 0.74 | AXL (0.40) | FGFR3CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026844-A9 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | REDDY US THERAPEUTICS INC (US) | 2004-11-11 | — | — | WO | claimed |