Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 2/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.42 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 7/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | CCKAR | P32238 | 1/20 | 0.35 |
| ▸ | CCKBR | P32239 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14142265 | 1.00 | DDB1 (0.42) | DDB1CRBNMAP1LC3BKMT2AKLK5 | |
| SCHEMBL7742010 | 0.91 | DDB1 (0.43) | DDB1CRBNKMT2AKLK5TLR2 | |
| SCHEMBL14142266 | 0.87 | KMT2A (0.43) | DDB1CRBNKMT2ASCN9AMEN1 | |
| SCHEMBL14294650 | 0.86 | SCN9A (0.49) | KMT2ASCN9ACCKARCCKBR | |
| SCHEMBL14294653 | 0.86 | MAP1LC3B (0.39) | DDB1CRBNMAP1LC3BKMT2A | |
| SCHEMBL14142180 | 0.86 | MAP1LC3B (0.39) | DDB1CRBNMAP1LC3BKMT2A | |
| SCHEMBL14141937 | 0.83 | MAP1LC3B (0.36) | DDB1CRBNMAP1LC3BKMT2ACYP3A4 | |
| SCHEMBL14294711 | 0.83 | MAP1LC3B (0.36) | DDB1CRBNMAP1LC3BKMT2ACYP3A4 | |
| SCHEMBL22143891 | 0.83 | DDB1 (0.45) | DDB1CRBNKMT2AMEN1CYP3A4 | |
| Hydrochloric Acid SCHEMBL14142396 | 0.82 | MAP1LC3B (0.36) | DDB1CRBNMAP1LC3BKMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8637545-B2 | Piperidine-2, 6-dione derivatives and their use as tumor necrosis factor inhibitors | TIANJIN HEMAY BIO-TECH CO., LTD. (CN) | 2014-01-28 | — | — | US | disclosed |
| US-20080051432-A1 | PIPERIDINE-2, 6-DIONE DERIVATIVES AND THEIR USE AS TUMOR NECROSIS FACTOR INHIBITORS | TIANJIN HEMAY PHARMACEUTICAL CO., LTD. (CN) | 2008-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051432-A1 | PIPERIDINE-2, 6-DIONE DERIVATIVES AND THEIR USE AS TUMOR NECROSIS FACTOR INHIBITORS | TNF, TNFRSF1A, TNFRSF9 | DDB1 2336/4885CRBN 896/4885MAP1LC3B 4651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.