Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.42 |
| ▸ | HTR2A | P28223 | 5/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.42 |
| ▸ | HRH1 | P35367 | 5/20 | 0.42 |
| ▸ | DRD3 | P35462 | 5/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 4/20 | 0.42 |
| ▸ | DRD4 | P21917 | 4/20 | 0.42 |
| ▸ | DRD5 | P21918 | 4/20 | 0.42 |
| ▸ | HRH2 | P25021 | 4/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.42 |
| ▸ | HTR7 | P34969 | 4/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.42 |
| ▸ | HTR6 | P50406 | 4/20 | 0.42 |
| ▸ | CACNA1D | Q01668 | 4/20 | 0.42 |
| ▸ | CACNA1S | Q13698 | 4/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 4/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.42 |
| ▸ | HTR2C | P28335 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4289692 | 0.85 | SLC6A3 (0.43) | SLC6A3HTR2AADRA1AHRH1DRD3 | |
| SCHEMBL8236341 | 0.85 | SLC6A3 (0.43) | SLC6A3HTR2AADRA1AHRH1DRD3 | |
| SCHEMBL7264075 | 0.67 | ACE (0.53) | HTR2CRAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7264101 | 0.67 | ACE (0.53) | HTR2CRAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20701593 | 0.66 | FKBP1A (0.47) | HTR2CRAB9ASMN1; SMN2 | |
| SCHEMBL31107769 | 0.66 | FKBP1A (0.47) | HTR2CRAB9ASMN1; SMN2 | |
| SCHEMBL15134222 | 0.66 | FKBP1A (0.47) | HTR2CRAB9ASMN1; SMN2 | |
| SCHEMBL10387196 | 0.65 | HTR2C (0.51) | HTR2CRAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10387195 | 0.65 | HTR2C (0.51) | HTR2CRAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8233700 | 0.65 | HTR2C (0.53) | HTR2CMAPK1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120322830-A1 | Cyclourea Compounds as Calcium Channel Blockers | PURDUE PHARMA L.P. (US) | 2012-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120322830-A1 | Cyclourea Compounds as Calcium Channel Blockers | CACNA1E, CACNA1B, CACNA1D | SLC6A3 640/4885HTR2A 2172/4885ADRA1A 399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.