Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13108643 | 0.90 | RORC (0.39) | GAARORC | |
| SCHEMBL12345114 | 0.85 | STAT3 (0.32) | MEN1KMT2AKDM4EGAAMAPT | |
| SCHEMBL14300268 | 0.85 | GAA (0.31) | MEN1KMT2AKDM4EGAAMAPT | |
| SCHEMBL27777714 | 0.82 | RORC (0.40) | GAARORC | |
| SCHEMBL13108632 | 0.82 | RORC (0.40) | GAARORC | |
| SCHEMBL12345098 | 0.81 | AR (0.36) | GAARORC | |
| SCHEMBL13108641 | 0.80 | RORC (0.40) | MEN1KMT2AKDM4EGAAMAPT | |
| SCHEMBL13108636 | 0.79 | AR (0.38) | GAARORC | |
| SCHEMBL13108623 | 0.78 | AR (0.40) | GAARORC | |
| SCHEMBL27756886 | 0.78 | AR (0.40) | GAARORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014134566-A2 | THERAPEUTIC COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2014-09-04 | — | — | WO | disclosed |
| WO-2008021796-A2 | PYRROLIDINONE ANILINES AS PROGESTERONE RECEPTOR MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-02-21 | — | — | WO | disclosed |