Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | MMP14 | P50281 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27777719 | 0.89 | AR (0.40) | GAAALDH1A1LMNAARRORC | |
| SCHEMBL12345110 | 0.89 | AR (0.40) | GAAALDH1A1LMNAARRORC | |
| SCHEMBL14300404 | 0.85 | MEN1 (0.31) | GAAMAPTNPSR1MEN1KMT2A | |
| SCHEMBL12345092 | 0.84 | RAB9A (0.36) | GAAMAPTNPSR1ALDH1A1LMNA | |
| SCHEMBL13108599 | 0.79 | AAK1 (0.36) | GAAMAPTALDH1A1ARKDM4E | |
| SCHEMBL28779023 | 0.79 | AR (0.43) | GAAALDH1A1LMNAARRORC | |
| SCHEMBL13108620 | 0.79 | AR (0.43) | GAAALDH1A1LMNAARRORC | |
| SCHEMBL13108623 | 0.77 | AR (0.40) | GAAALDH1A1LMNAARRORC | |
| SCHEMBL27756886 | 0.77 | AR (0.40) | GAAALDH1A1LMNAARRORC | |
| SCHEMBL12345120 | 0.77 | RORC (0.40) | GAAALDH1A1LMNAARRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021796-A2 | PYRROLIDINONE ANILINES AS PROGESTERONE RECEPTOR MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-02-21 | — | — | WO | disclosed |