Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVR1 | Q04771 | 4/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.49 |
| ▸ | SRPK1 | Q96SB4 | 3/20 | 0.49 |
| ▸ | CDK1 | P06493 | 3/20 | 0.49 |
| ▸ | CDK2 | P24941 | 3/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.49 |
| ▸ | STK3 | Q13188 | 3/20 | 0.49 |
| ▸ | PIM3 | Q86V86 | 3/20 | 0.49 |
| ▸ | HIPK4 | Q8NE63 | 3/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.49 |
| ▸ | HIPK2 | Q9H2X6 | 3/20 | 0.49 |
| ▸ | PTK6 | Q13882 | 2/20 | 0.49 |
| ▸ | MINK1 | Q8N4C8 | 2/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.49 |
| ▸ | CLK2 | P49760 | 2/20 | 0.49 |
| ▸ | PLK4 | O00444 | 1/20 | 0.49 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.49 |
| ▸ | RET | P07949 | 1/20 | 0.49 |
| ▸ | ROS1 | P08922 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14300151 | 0.84 | RORC (0.46) | ACVR1CLK4SRPK1CDK1CDK2 | |
| SCHEMBL1465896 | 0.80 | PLK4 (0.49) | ACVR1CLK4SRPK1CDK1CDK2 | |
| SCHEMBL16359172 | 0.76 | GSK3A (0.44) | ACVR1CLK4SRPK1CDK1CDK2 | |
| SCHEMBL1464316 | 0.75 | GSK3A (0.49) | ACVR1CLK4SRPK1CDK1CDK2 | |
| SCHEMBL14300149 | 0.74 | CLK4 (0.50) | ACVR1CLK4SRPK1CDK1CDK2 | |
| SCHEMBL14960342 | 0.73 | GSK3A (0.48) | ACVR1CLK4SRPK1CDK1CDK2 | |
| SCHEMBL14302166 | 0.71 | KMT2A (0.61) | NPC1RAB9AMAPTTSHRSMN1; SMN2 | |
| SCHEMBL13170010 | 0.70 | KDM4E (0.56) | ACVR1CLK4SRPK1CDK1CDK2 | |
| SCHEMBL1621426 | 0.69 | RORC (0.49) | ACVR1CLK4SRPK1CDK1CDK2 | |
| SCHEMBL10068147 | 0.69 | GAA (0.51) | ACVR1CLK4SRPK1CDK1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080039464-A1 | Compounds Which Modulate The CB2 Receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039464-A1 | Compounds Which Modulate The CB2 Receptor | CNR2, CNR1, OPRL1 | ACVR1 2952/4885CLK4 3562/4885SRPK1 4263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.