Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.52 |
| ▸ | GSK3A | P49840 | 5/20 | 0.52 |
| ▸ | GSK3B | P49841 | 5/20 | 0.52 |
| ▸ | SRPK1 | Q96SB4 | 4/20 | 0.52 |
| ▸ | AURKA | O14965 | 1/20 | 0.52 |
| ▸ | PRKX | P51817 | 1/20 | 0.52 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.52 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.52 |
| ▸ | GRM5 | P41594 | 2/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 8/20 | 0.49 |
| ▸ | ACVR1 | Q04771 | 7/20 | 0.49 |
| ▸ | HIPK4 | Q8NE63 | 5/20 | 0.49 |
| ▸ | STK3 | Q13188 | 4/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.49 |
| ▸ | FLT3 | P36888 | 3/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2635287 | 0.84 | TAS2R14 (0.57) | TAS2R14GSK3AGSK3BSRPK1AURKA | |
| SCHEMBL10183380 | 0.84 | KDM4E (0.57) | KDM4ELMNAGRM5MAPK8SYK | |
| SCHEMBL29640129 | 0.83 | P2RX7 (0.53) | TAS2R14GSK3AGSK3BSRPK1AURKA | |
| SCHEMBL5031654 | 0.83 | P2RX7 (0.53) | TAS2R14GSK3AGSK3BSRPK1AURKA | |
| SCHEMBL13591378 | 0.83 | KDM4E (0.56) | KDM4ELMNAMAPK8SYK | |
| SCHEMBL1464316 | 0.82 | GSK3A (0.49) | TAS2R14GSK3AGSK3BSRPK1AURKA | |
| SCHEMBL9891927 | 0.82 | GSK3A (0.52) | TAS2R14GSK3AGSK3BSRPK1AURKA | |
| SCHEMBL18425134 | 0.82 | ACVR1 (0.49) | TAS2R14GSK3AGSK3BSRPK1AURKA | |
| SCHEMBL821844 | 0.81 | KDM4E (0.71) | KDM4ELMNAGRM5MAPK8 | |
| SCHEMBL14960342 | 0.81 | GSK3A (0.48) | TAS2R14GSK3AGSK3BSRPK1AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8629157-B2 | Pyrrolidine compounds which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-01-14 | — | — | US | disclosed |
| US-8449898-B2 | Fungicidal mixtures | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-05-28 | — | — | US | disclosed |
| US-8449898-B2 | Fungicidal mixtures | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-05-28 | — | — | US | disclosed |
| US-20100240619-A1 | FUNGICIDAL MIXTURES | CORTEVA AGRISCIENCE LLC | 2010-09-23 | — | — | US | disclosed |
| US-20100240619-A1 | FUNGICIDAL MIXTURES | CORTEVA AGRISCIENCE LLC | 2010-09-23 | — | — | US | disclosed |
| WO-2009055514-A2 | FUNGICIDAL MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-04-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240619-A1 | FUNGICIDAL MIXTURES | CYP1B1, CYP1A1, NOX1 | KDM4E 2105/4885LMNA 2648/4885TAS2R14 3737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.