SCHEMBL143032

SCHEMBL143032

CC(C)OC(=O)[C@@H](C)N(C(=O)c1ccccc1)c1ccc(F)c(Cl)c1

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
MDM4 O15151 2/20 0.39
MDM2 Q00987 2/20 0.39
MEN1 O00255 1/20 0.39
PLA2G1B P04054 1/20 0.39
HTT P42858 1/20 0.39
KMT2A Q03164 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
ATG4B Q9Y4P1 1/20 0.39
PTGIR P43119 1/20 0.39
TRPM8 Q7Z2W7 1/20 0.37
MLYCD O95822 1/20 0.37
ALDH1A1 P00352 1/20 0.37
PDK1 Q15118 3/20 0.36
HDAC8 Q9BY41 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5404448 1.00 NPC1 (0.44) NPC1RAB9AMDM4MDM2MEN1
SCHEMBL143033 1.00 NPC1 (0.44) NPC1RAB9AMDM4MDM2MEN1
SCHEMBL29512563 1.00 NPC1 (0.44) NPC1RAB9AMDM4MDM2MEN1
SCHEMBL29796373 1.00 NPC1 (0.44) NPC1RAB9AMDM4MDM2MEN1
SCHEMBL8674776 0.96 NPC1 (0.41) NPC1RAB9AMDM4MDM2MEN1
SCHEMBL932528 0.95 MEN1 (0.46) NPC1RAB9AMDM4MDM2MEN1
SCHEMBL11597125 0.90 NPC1 (0.41) NPC1RAB9AMEN1KMT2APTGIR
SCHEMBL30519772 0.89 MEN1 (0.51) NPC1RAB9AMDM4MDM2MEN1
SCHEMBL29435442 0.89 MEN1 (0.51) NPC1RAB9AMDM4MDM2MEN1
SCHEMBL55267 0.89 MEN1 (0.51) NPC1RAB9AMDM4MDM2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4361 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4713317-A1 A PROCESS FOR PURIFICATION OF ETHOFUMESATE Adama Agan Ltd. (IL) 2026-03-25 EP claimed
US-20260060254-A1 HERBICIDAL COMPOSITIONS BAYER AG (DE) 2026-03-05 US claimed
US-20260007133-A1 HERBICIDAL COMPOSITION COMPRISING AZINE COMPOUNDS BASF SE (DE) 2026-01-08 US claimed
EP-3060043-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CORTEVA AGRISCIENCE LLC (US) 2025-11-26 EP claimed
EP-4178357-B1 METHOD FOR CONTROLLING UNDESIRABLE VEGETATION IN AN AQUATIC ENVIRONMENT BASF AGRO BV (NL) 2025-09-24 EP claimed
EP-4593598-A1 STORAGE-STABLE COMPOSITIONS INCLUDING BIXLOZONE AND BEFLUBUTAMID FMC Corporation (US) 2025-08-06 EP claimed
US-12376586-B2 Microcapsules comprising cinmethyln in the core and a polyurea derived from diphenylmethane diisocyanate or an oligomer thereof BASF Agro B.V. (NL) 2025-08-05 US claimed
US-20250241298-A1 Liquid Sulfonylurea-Containing Herbicidal Compositions BATTELLE UK LIMITED (GB) 2025-07-31 US claimed
EP-4577047-A1 HERBICIDAL COMPOSITIONS Bayer Aktiengesellschaft (DE) 2025-07-02 EP claimed
EP-4566449-A1 HERBICIDE COMPOSITION COMPRISING URACIL COMPOUND COMPRISING CARBOXYLATE FRAGMENT AND USE OF HERBICIDE COMPOSITION Jiangsu Flag Chemical Industry Co., Ltd (CN) 2025-06-11 EP claimed
US-5985799-A TRICYCLIC N-HETEROCYCLES, THEIR N-OXIDES, AGRICULTURALLY-SUITABLE SALTS AND COMPOSITIONS, AND METHODS OF THEIR USE FOR CONTROLLING UNDESIRABLE VEGETATION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-11-16 US claimed
EP-0876375-A1 TRICYCLIC HERBICIDAL HETEROCYCLES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-11-11 EP claimed
EP-0862571-A1 HERBICIDAL SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-09-09 EP claimed
WO-1997019087-A1 TRICYCLIC HERBICIDAL HETEROCYCLES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-05-29 WO claimed
WO-1997015576-A1 HERBICIDAL SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-05-01 WO claimed
EP-0407341-B1 Selective herbicidal agent CIBA GEIGY AG (CH) 1995-12-06 EP claimed
EP-0274892-B1 METHOD OF KILLING WEEDS COMPRISING THE USE OF DIFLUFENICAN MAY & BAKER LIMITED (GB) 1992-08-12 EP claimed
US-5059239-A Preemergence; postemergence; grains CIBA-GEIGY CORPORATION (US) 1991-10-22 US claimed
EP-0407341-A1 Selective herbicidal agent CIBA-GEIGY AG (CH) 1991-01-09 EP claimed
EP-0274892-A2 Method of killing weeds comprising the use of diflufenican MAY & BAKER LIMITED (GB) 1988-07-20 EP claimed