Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MDM4 | O15151 | 2/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | PTGIR | P43119 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29796373 | 0.96 | NPC1 (0.44) | NPC1RAB9AMDM4MDM2MEN1 | |
| SCHEMBL143033 | 0.96 | NPC1 (0.44) | NPC1RAB9AMDM4MDM2MEN1 | |
| SCHEMBL143032 | 0.96 | NPC1 (0.44) | NPC1RAB9AMDM4MDM2MEN1 | |
| SCHEMBL5404448 | 0.96 | NPC1 (0.44) | NPC1RAB9AMDM4MDM2MEN1 | |
| SCHEMBL29512563 | 0.96 | NPC1 (0.44) | NPC1RAB9AMDM4MDM2MEN1 | |
| SCHEMBL932528 | 0.92 | MEN1 (0.46) | NPC1RAB9AMDM4MDM2MEN1 | |
| SCHEMBL4894601 | 0.91 | NPC1 (0.46) | NPC1RAB9AMDM4MDM2NPSR1 | |
| SCHEMBL9370834 | 0.91 | NPC1 (0.46) | NPC1RAB9AMDM4MDM2NPSR1 | |
| SCHEMBL4454349 | 0.91 | NPC1 (0.46) | NPC1RAB9AMDM4MDM2NPSR1 | |
| SCHEMBL6013579 | 0.91 | NPC1 (0.46) | NPC1RAB9AMDM4MDM2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837651-A | SURFACTANTS, UREA, PESTICIDE OR PLANT GROWTH REGULATOR AS ACTIVE INGREDIENT; DELIVERING TO AGRICULTURAL OR HORTICULTURAL LOCUS | AMERICAN CYANAMID COMPANY (US) | 1998-11-17 | — | — | US | disclosed |
| US-5709871-A | WATER DISPERSIBLE; MIXTURE OF SURFACTANTS AND UREA | SHELL RESEARCH LIMITED (GB) | 1998-01-20 | — | — | US | disclosed |