Sugi Predict

Sugi Predict / Compounds / SCHEMBL932528

SCHEMBL932528

SCHEMBL932528

CC(C)OC(=O)[C@@H](C)N(C(=O)c1ccccc1)c1ccc(F)c(Cl)c1.COC(=O)C(C)N(C(=O)c1ccccc1)c1ccc(F)c(Cl)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.46
▸ KMT2A Q03164 2/20 0.46
▸ PLA2G1B P04054 1/20 0.46
▸ HTT P42858 1/20 0.46
▸ NPSR1 Q6W5P4 1/20 0.46
▸ ATG4B Q9Y4P1 1/20 0.46
▸ NPC1 O15118 2/20 0.43
▸ RAB9A P51151 2/20 0.43
▸ MDM4 O15151 2/20 0.41
▸ MDM2 Q00987 2/20 0.41
▸ PTGIR P43119 1/20 0.36
▸ HDAC8 Q9BY41 1/20 0.36
▸ MAPT P10636 1/20 0.36
▸ CASP3 P42574 1/20 0.36
▸ SENP7 Q9BQF6 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.35
▸ USP2 O75604 1/20 0.35
▸ LMNA P02545 1/20 0.35
▸ PTGS1 P23219 1/20 0.35
▸ PTGS2 P35354 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL143032 0.95 NPC1 (0.44) MEN1KMT2APLA2G1BHTTNPSR1
SCHEMBL143033 0.95 NPC1 (0.44) MEN1KMT2APLA2G1BHTTNPSR1
SCHEMBL29512563 0.95 NPC1 (0.44) MEN1KMT2APLA2G1BHTTNPSR1
SCHEMBL5404448 0.95 NPC1 (0.44) MEN1KMT2APLA2G1BHTTNPSR1
SCHEMBL29796373 0.95 NPC1 (0.44) MEN1KMT2APLA2G1BHTTNPSR1
SCHEMBL635027 0.94 MEN1 (0.51) MEN1KMT2APLA2G1BHTTNPSR1
SCHEMBL55267 0.94 MEN1 (0.51) MEN1KMT2APLA2G1BHTTNPSR1
SCHEMBL29435442 0.94 MEN1 (0.51) MEN1KMT2APLA2G1BHTTNPSR1
SCHEMBL30519772 0.94 MEN1 (0.51) MEN1KMT2APLA2G1BHTTNPSR1
SCHEMBL8827406 0.94 MEN1 (0.51) MEN1KMT2APLA2G1BHTTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2157856-A1 HERBICIDALLY EFFECTIVE COMPOSITION Basf Se (DE) 2010-03-03 — — EP claimed
WO-2008152074-A1 HERBICIDALLY EFFECTIVE COMPOSITION BASF SE (DE) 2008-12-18 — — WO claimed
US-11248234-B2 Herbicide-resistant hydroxyphenylpyruvate dioxygenases BASF SE (DE) 2022-02-15 — — US disclosed
US-11230717-B2 Plants having increased tolerance to herbicides BASF SE (DE) 2022-01-25 — — US disclosed
US-11046971-B2 Plants having increased tolerance to herbicides BASF SE 2021-06-29 — — US disclosed
US-20210147866-A1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES BASF SE (DE) 2021-05-20 — — US disclosed
US-10881109-B2 Herbicidal compositions comprising isoxazolo[5,4-b]pyridines BASF SE (DE) 2021-01-05 — — US disclosed
US-10829778-B2 Plants having increased tolerance to herbicides BASF SE (DE) 2020-11-10 — — US disclosed
US-10619138-B2 Herbicide-resistant hydroxyphenylpyruvate dioxygenases BASF SE (DE) 2020-04-14 — — US disclosed
US-20190150448-A1 Herbicidal Compositions Comprising Isoxazolo[5,4-B]Pyridines BASF SE (DE) 2019-05-23 — — US disclosed
WO-2018235005-A1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES BASF SE (DE) 2018-12-27 — — WO disclosed
WO-2010139657-A1 SUBSTITUTED PYRAZINE (THIO)PYRANS WITH A HERBICIDAL ACTION BASF SE (DE) 2010-12-09 — — WO disclosed
WO-2010069802-A1 HETEROCYCLIC DIKETONE DERIVATIVES WITH HERBICIDAL ACTION BASF SE (DE) 2010-06-24 — — WO disclosed
WO-2010066677-A2 HERBICIDAL MIXTURES BASF SE (DE) 2010-06-17 — — WO disclosed
WO-2010066679-A2 HERBICIDAL MIXTURES BASF SE (DE) 2010-06-17 — — WO disclosed
WO-2010049270-A1 SUBSTITUTED PYRIDINES HAVING A HERBICIDAL EFFECT BASF SE (DE) 2010-05-06 — — WO disclosed
WO-2010049269-A1 SUBSTITUTED PYRIDINES HAVING A HERBICIDAL EFFECT BASF SE (DE) 2010-05-06 — — WO disclosed
WO-2010049369-A1 PIPERAZINE COMPOUNDS WITH HERBICIDAL EFFECT BASF SE (DE) 2010-05-06 — — WO disclosed
WO-2010037727-A1 PIPERAZINE COMPOUNDS WITH HERBICIDAL EFFECT BASF SE (DE) 2010-04-08 — — WO disclosed
WO-2010012649-A1 PIPERAZINE COMPOUNDS WITH HERBICIDAL EFFECT BASF SE (DE) 2010-02-04 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190150448-A1 Herbicidal Compositions Comprising Isoxazolo[5,4-B]Pyridines CYP4X1, CYP4Z1, PRDX4 MEN1 4881/4885KMT2A 2306/4885PLA2G1B 833/4885
US-10829778-B2 Plants having increased tolerance to herbicides HPD, MPST, NMT2 MEN1 4709/4885KMT2A 195/4885PLA2G1B 2984/4885
US-11230717-B2 Plants having increased tolerance to herbicides HPD, MPST, DNTT MEN1 4580/4885KMT2A 283/4885PLA2G1B 3587/4885
US-20210147866-A1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES HPD, PAH, ME3 MEN1 4289/4885KMT2A 244/4885PLA2G1B 4200/4885
US-10881109-B2 Herbicidal compositions comprising isoxazolo[5,4-b]pyridines CYP4X1, CYP4Z1, PRDX4 MEN1 4882/4885KMT2A 2373/4885PLA2G1B 883/4885
US-11046971-B2 Plants having increased tolerance to herbicides HPD, MPST, DNTT MEN1 4580/4885KMT2A 283/4885PLA2G1B 3587/4885
US-10619138-B2 Herbicide-resistant hydroxyphenylpyruvate dioxygenases HPD, PHPT1, DERA MEN1 4532/4885KMT2A 661/4885PLA2G1B 3399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.