SCHEMBL14304589

SCHEMBL14304589

Cn1c2ccccc2c2cc(/C=N/N(CC3CO3)c3ccc(S(=O)(=O)c4ccc(N(CC5CO5)/N=C/c5ccc6c(c5)c5ccccc5n6C)cc4)cc3)ccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.38
MEN1 O00255 7/20 0.38
POLB P06746 6/20 0.38
APOBEC3A P31941 1/20 0.38
RAB9A P51151 1/20 0.38
APOBEC3G Q9HC16 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
KDM4E B2RXH2 6/20 0.38
HTT P42858 2/20 0.38
PKM P14618 1/20 0.38
MAPT P10636 3/20 0.37
CASP6 P55212 1/20 0.36
CACNA1B Q00975 1/20 0.36
APBA1 Q02410 1/20 0.36
SRC P12931 2/20 0.36
ALDH1A1 P00352 6/20 0.36
HPGD P15428 6/20 0.36
LMNA P02545 5/20 0.36
SMN1; SMN2 Q16637 5/20 0.36
USP2 O75604 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14279681 0.92 KDM4E (0.48) KMT2AMEN1POLBKDM4EHTT
SCHEMBL3982985 0.81 KDM4E (0.55) KMT2AMEN1POLBTDP1KDM4E
SCHEMBL3985543 0.81 KDM4E (0.55) KMT2AMEN1POLBTDP1KDM4E
SCHEMBL14254910 0.78 LMNA (0.44) KMT2AMEN1POLBRAB9ATDP1
SCHEMBL4832507 0.77 KDM4E (0.49) KMT2AMEN1POLBKDM4EHTT
SCHEMBL14254907 0.77 KDM4E (0.49) KMT2AMEN1POLBKDM4EHTT
SCHEMBL14491195 0.77 KDM4E (0.38) KMT2AMEN1POLBRAB9ATDP1
SCHEMBL14355045 0.77 KDM4E (0.50) KMT2AMEN1POLBTDP1KDM4E
SCHEMBL14099141 0.75 MEN1 (0.42) KMT2AMEN1POLBAPOBEC3ARAB9A
SCHEMBL14593714 0.75 SRC (0.39) KMT2AMEN1POLBKDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7320849-B2 Organophotoreceptor with a charge transport material having two epoxidated-hydrazone groups SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-01-22 US disclosed