SCHEMBL3982985

SCHEMBL3982985

CCn1c2ccccc2c2cc(C=NN(CC3CO3)c3ccccc3)ccc21

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.55
POLB P06746 4/20 0.55
HTT P42858 3/20 0.55
PKM P14618 1/20 0.55
SRC P12931 4/20 0.53
ALDH1A1 P00352 9/20 0.50
HPGD P15428 8/20 0.50
SMN1; SMN2 Q16637 7/20 0.50
MAPT P10636 7/20 0.50
LMNA P02545 5/20 0.50
HSD17B10 Q99714 2/20 0.50
USP2 O75604 1/20 0.50
TSHR P16473 1/20 0.50
CASP1 P29466 1/20 0.50
MEN1 O00255 7/20 0.48
KMT2A Q03164 7/20 0.48
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
GAA P10253 1/20 0.45
CYP2C9 P11712 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3985543 1.00 KDM4E (0.55) KDM4EPOLBHTTPKMSRC
SCHEMBL14254907 0.97 KDM4E (0.49) KDM4EPOLBHTTPKMSRC
SCHEMBL4832507 0.97 KDM4E (0.49) KDM4EPOLBHTTPKMSRC
SCHEMBL14279681 0.90 KDM4E (0.48) KDM4EPOLBHTTPKMSRC
SCHEMBL14355045 0.89 KDM4E (0.50) KDM4EPOLBHTTPKMSRC
SCHEMBL14355049 0.87 KDM4E (0.43) KDM4EPOLBHTTPKMSRC
SCHEMBL4820424 0.87 KDM4E (0.54) KDM4EPOLBHTTPKMSRC
SCHEMBL4820428 0.87 KDM4E (0.54) KDM4EPOLBHTTPKMSRC
SCHEMBL14355047 0.86 KDM4E (0.45) KDM4EPOLBHTTPKMSRC
SCHEMBL1702588 0.86 KDM4E (0.63) KDM4EPOLBHTTPKMSRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7534541-B2 Heterocycle-hydrazone based charge transport materials SAMSUNG ELECTRONICS CO., LTD. (KR) 2009-05-19 US disclosed
US-7445877-B2 Charge transport materials having a central disulfane linkage SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-11-04 US disclosed
US-7326506-B2 Bridged charge transport materials having a central sulfur atom linkage SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-02-05 US disclosed
US-7244541-B2 Linked dihydrazone-based charge transport compounds SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-07-17 US disclosed
EP-1519235-B1 Linked dihydrazone-based charge transport compounds SAMSUNG ELECTRONICS CO LTD (KR) 2007-07-11 EP disclosed
EP-1600821-B1 Bridged charge transport materials having a central sulfur atom linkage SAMSUNG ELECTRONICS CO LTD (KR) 2007-02-28 EP disclosed
US-20060166118-A1 Heterocycle-hydrazone based charge transport materials S-PRINTING SOLUTION CO., LTD. (KR) 2006-07-27 US disclosed
US-7074532-B2 Linked dihydrazone-based charge transport compounds SAMSUNG ELECTRONICS, CO., LTD. (KR) 2006-07-11 US disclosed
US-20060127794-A1 Linked dihydrazone-based charge transport compounds SAMSUNG ELECTRONICS CO., LTD 2006-06-15 US disclosed
US-7014968-B2 Organophotoreceptor with charge transport material having a thiiranyl group SAMSUNG ELECTRONICS CO., LTD. (KR) 2006-03-21 US disclosed
EP-1550913-A1 Organophotoreceptor with charge transport material having a thiiranyl group Samsung Electronics Co., Ltd. (KR) 2005-07-06 EP disclosed
US-6899984-B2 Linked dihydrazone-based charge transport compounds SAMSUNG ELECTRONICS CO., LTD. (KR) 2005-05-31 US disclosed
EP-1519235-A2 Linked dihydrazone-based charge transport compounds Samsung Electronics Co., Ltd. (KR) 2005-03-30 EP disclosed
US-20050058916-A1 Linked dihydrazone-based charge transport compounds S-PRINTING SOLUTION CO., LTD. (KR) 2005-03-17 US disclosed
US-20040152002-A1 Organophotoreceptor with charge transport material having two linked hydrazone groups SAMSUNG ELECTRONICS CO., LTD. (KR) 2004-08-05 US disclosed
EP-1443039-A1 Organophotoreceptor with charge transport material having two linked hydrazone groups Samsung Electronics Co., Ltd. (KR) 2004-08-04 EP disclosed
US-20030232264-A1 Linked dihydrazone-based charge transport compounds HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2003-12-18 US disclosed
US-20030232261-A1 Linked dihydrazone-based charge transport compounds S-PRINTING SOLUTION CO., LTD. (KR) 2003-12-18 US disclosed
WO-2001046757-A1 ORGANOPHOTORECEPTORS FOR ELECTROPHOTOGRAPHY COMPRISING CHARGE TRANSPORT COMPOUNDS BASED UPON HYDROXY-FUNCTIONAL COMPOUNDS IMATION CORP. (US) 2001-06-28 WO disclosed
US-6214503-B1 Organophotoreceptors for electrophotography featuring novel charge transport compounds based upon hydroxy-functional compounds IMATION CORP. 2001-04-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060166118-A1 Heterocycle-hydrazone based charge transport materials AQP1, SLC9B2, SLC9A2 KDM4E 2960/4885POLB 3855/4885HTT 771/4885
US-20030232264-A1 Linked dihydrazone-based charge transport compounds SLC43A1, SLC26A3, SLC22A8 KDM4E 2572/4885POLB 2631/4885HTT 1410/4885
US-20030232261-A1 Linked dihydrazone-based charge transport compounds SLC43A1, SLC22A8, SLC6A19 KDM4E 3368/4885POLB 4217/4885HTT 1328/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.