Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 9/20 | 0.46 |
| ▸ | CA12 | O43570 | 8/20 | 0.46 |
| ▸ | CA1 | P00915 | 8/20 | 0.46 |
| ▸ | CA9 | Q16790 | 8/20 | 0.46 |
| ▸ | TLR4 | O00206 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30718114 | 0.89 | LMNA (0.63) | LMNAKMT2APOLBALDH1A1CYP2D6 | |
| SCHEMBL25716867 | 0.88 | LMNA (0.67) | LMNAKMT2APOLBALDH1A1CYP2D6 | |
| SCHEMBL20788116 | 0.87 | LMNA (0.61) | LMNAKMT2APOLBALDH1A1CYP2D6 | |
| SCHEMBL15333976 | 0.87 | LMNA (0.61) | LMNAKMT2APOLBALDH1A1CYP2D6 | |
| SCHEMBL30032874 | 0.87 | LMNA (0.65) | LMNAKMT2APOLBALDH1A1CYP2D6 | |
| SCHEMBL21058368 | 0.87 | LMNA (0.65) | LMNAKMT2APOLBALDH1A1CYP2D6 | |
| SCHEMBL21138671 | 0.87 | LMNA (0.65) | LMNAKMT2APOLBALDH1A1CYP2D6 | |
| SCHEMBL25957762 | 0.87 | LMNA (0.65) | LMNAKMT2APOLBALDH1A1CYP2D6 | |
| SCHEMBL9524271 | 0.84 | CA1 (0.49) | LMNAKMT2APOLBALDH1A1CYP2D6 | |
| SCHEMBL9735191 | 0.84 | CA1 (0.49) | LMNAKMT2APOLBALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008007153-A2 | ANTIVIRAL COMPOUNDS | IQUR LTD. (GB) | 2008-01-17 | — | — | WO | disclosed |