Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 7/20 | 0.49 |
| ▸ | CA2 | P00918 | 7/20 | 0.49 |
| ▸ | CA9 | Q16790 | 7/20 | 0.49 |
| ▸ | CA12 | O43570 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PRKCA | P17252 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.47 |
| ▸ | MMP12 | P39900 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735191 | 1.00 | CA1 (0.49) | CA1CA2CA9CA12LMNA | |
| SCHEMBL16392573 | 0.91 | CA1 (0.49) | CA1CA2CA9CA12LMNA | |
| SCHEMBL16392618 | 0.89 | LMNA (0.50) | CA1CA2CA9CA12LMNA | |
| SCHEMBL16009284 | 0.89 | CA12 (0.59) | CA1CA2CA9CA12PRKCA | |
| SCHEMBL21133688 | 0.87 | LMNA (0.50) | CA1CA2CA9CA12LMNA | |
| SCHEMBL24997325 | 0.87 | LMNA (0.48) | CA1CA2CA9CA12LMNA | |
| SCHEMBL14304830 | 0.84 | LMNA (0.62) | CA1CA2CA9CA12LMNA | |
| SCHEMBL16392904 | 0.84 | LMNA (0.51) | CA1CA2CA9CA12LMNA | |
| SCHEMBL22559700 | 0.81 | LMNA (0.55) | CA1CA2CA9CA12LMNA | |
| SCHEMBL4616897 | 0.81 | CA12 (0.52) | CA1CA2CA9CA12LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533692-A1 | MITOMYCIN DERIVATIVES HAVING REDUCED BONE MARROW TOXICITY, PROCESSES FOR THEIR PREPARATION, AND THE USES THEREOF | GEORGETOWN UNIVERSITY (US) | 1993-03-31 | — | — | EP | disclosed |
| US-5091523-A | Bactericides, antitumor agent | GEORGETOWN UNIVERSITY (US) | 1992-02-25 | — | — | US | disclosed |
| WO-1991016049-A1 | MITOMYCIN DERIVATIVES HAVING REDUCED BONE MARROW TOXICITY, PROCESSES FOR THEIR PREPARATION, AND THE USES THEREOF | GEORGETOWN UNIVERSITY (US) | 1991-10-31 | — | — | WO | disclosed |