Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | GAA | P10253 | 7/20 | 0.50 |
| ▸ | USP2 | O75604 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | CASP1 | P29466 | 4/20 | 0.50 |
| ▸ | CASP7 | P55210 | 4/20 | 0.50 |
| ▸ | GLA | P06280 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.48 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22632115 | 0.88 | ALDH1A1 (0.56) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL3205404 | 0.86 | ALDH1A1 (0.51) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL24623962 | 0.84 | KMT2A (0.60) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL24623242 | 0.83 | ALDH1A1 (0.53) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL14303304 | 0.82 | KMT2A (0.60) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL24623305 | 0.78 | ALDH1A1 (0.64) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL22632114 | 0.78 | KMT2A (0.55) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL903151 | 0.77 | ALDH1A1 (0.68) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL3202594 | 0.76 | KMT2A (0.61) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL1212238 | 0.76 | ALDH1A1 (0.63) | ALDH1A1KDM4EMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008013997-A2 | FLUORESCENT SUBSTRATES FOR MONOAMINE TRANSPORTERS AS OPTICAL FALSE NEUROTRANSMITTERS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2008-01-31 | — | — | WO | disclosed |