Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 12/20 | 0.58 |
| ▸ | CD274 | Q9NZQ7 | 12/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL437878 | 0.82 | PDCD1 (0.54) | PDCD1CD274KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL30504422 | 0.80 | CD274 (0.68) | PDCD1CD274APEX1TLR9TLR8 | |
| SCHEMBL19549722 | 0.80 | PDCD1 (0.82) | PDCD1CD274CYP3A4 | |
| SCHEMBL6223472 | 0.79 | ALDH1A1 (0.49) | PDCD1CD274KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL407298 | 0.79 | PDCD1 (0.54) | PDCD1CD274NPC1MAPTRAB9A | |
| SCHEMBL20324274 | 0.79 | PDCD1 (0.66) | PDCD1CD274APEX1TLR9TLR8 | |
| Bromide SCHEMBL439705 | 0.78 | PDCD1 (0.53) | PDCD1CD274NPC1MAPTRAB9A | |
| SCHEMBL30504452 | 0.76 | CD274 (0.63) | PDCD1CD274APEX1TLR9TLR8 | |
| SCHEMBL17398106 | 0.74 | PDK1 (0.45) | PDCD1CD274KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL504649 | 0.74 | PDCD1 (0.49) | PDCD1CD274KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008011130-A2 | AMIDE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-01-24 | — | — | WO | disclosed |