Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 6/20 | 0.60 |
| ▸ | METTL3 | Q86U44 | 13/20 | 0.54 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20058772 | 0.89 | ADK (0.61) | ADK | |
| SCHEMBL10268710 | 0.89 | ADK (0.61) | ADK | |
| SCHEMBL20419234 | 0.88 | ADK (0.59) | ADKMETTL3RAPGEF3 | |
| SCHEMBL20938262 | 0.88 | ADK (0.59) | ADKMETTL3RAPGEF3 | |
| SCHEMBL20419136 | 0.88 | ADK (0.59) | ADKMETTL3RAPGEF3 | |
| SCHEMBL12151806 | 0.87 | ADK (0.47) | ADK | |
| SCHEMBL14313964 | 0.87 | ADK (0.47) | ADKMETTL3 | |
| SCHEMBL13952411 | 0.87 | ADK (0.60) | ADKMETTL3 | |
| SCHEMBL20059237 | 0.87 | ADK (0.47) | ADK | |
| SCHEMBL14154378 | 0.87 | ADK (0.60) | ADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7323453-B2 | Methods of inhibiting orthopoxvirus replication with nucleoside compounds | MERCK & CO., INC. (US) | 2008-01-29 | — | — | US | disclosed |