Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 14/20 | 0.47 |
| ▸ | METTL3 | Q86U44 | 3/20 | 0.43 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.42 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20058772 | 0.89 | ADK (0.61) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL10268710 | 0.89 | ADK (0.61) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL20938333 | 0.88 | ADK (0.46) | ADKMETTL3DOT1LNPC1GALR3 | |
| SCHEMBL14305600 | 0.87 | ADK (0.60) | ADKMETTL3 | |
| SCHEMBL14154378 | 0.87 | ADK (0.60) | ADKRAB9APRMT5 | |
| SCHEMBL12151806 | 0.87 | ADK (0.47) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL20059237 | 0.87 | ADK (0.47) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL14313959 | 0.85 | ADK (0.62) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL14544497 | 0.84 | ADK (0.53) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL10266528 | 0.84 | ADK (0.62) | ADKMETTL3DOT1LNPC1GALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7323453-B2 | Methods of inhibiting orthopoxvirus replication with nucleoside compounds | MERCK & CO., INC. (US) | 2008-01-29 | — | — | US | disclosed |