Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | CNR1 | P21554 | 1/20 | 0.67 |
| ▸ | CNR2 | P34972 | 1/20 | 0.67 |
| ▸ | NAMPT | P43490 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.60 |
| ▸ | HPGDS | O60760 | 1/20 | 0.60 |
| ▸ | FAAH | O00519 | 1/20 | 0.59 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.59 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.59 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.59 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.59 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.59 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6153200 | 0.98 | KMT2A (0.69) | MAPTCNR1CNR2NAMPTKMT2A | |
| SCHEMBL4559682 | 0.97 | MAPT (0.73) | MAPTCNR1CNR2NAMPTKMT2A | |
| SCHEMBL2097739 | 0.87 | MAPT (0.59) | MAPTCNR1CNR2NAMPTKMT2A | |
| SCHEMBL10253402 | 0.87 | CNR2 (0.88) | MAPTCNR1CNR2NAMPTKMT2A | |
| SCHEMBL3072567 | 0.87 | MAPT (0.59) | MAPTCNR1CNR2NAMPTKMT2A | |
| SCHEMBL15134839 | 0.86 | EPHX2 (0.69) | MAPTCNR1CNR2NAMPTKMT2A | |
| SCHEMBL655599 | 0.86 | POLB (0.63) | MAPTCNR1CNR2NAMPTTRPV1 | |
| SCHEMBL6764534 | 0.86 | NAMPT (0.61) | MAPTCNR1CNR2NAMPTEPHX2 | |
| SCHEMBL28363944 | 0.86 | SMN1; SMN2 (0.70) | MAPTCNR1CNR2NAMPTKMT2A | |
| Hydrochloric Acid SCHEMBL23246046 | 0.84 | POLB (0.66) | MAPTCNR1CNR2NAMPTTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110878070-B | Method for preparing asymmetric urea compound | 中国科学院化学研究所 | 2021-08-31 | — | — | CN | disclosed |
| CN-110878070-A | Method for preparing asymmetric urea compound | 中国科学院化学研究所 | 2020-03-13 | — | — | CN | disclosed |
| WO-2008011392-A2 | PROLINE UREA CCR1 ANTAGONISTS FOR THE TREATMENT OF AUTOIMMUNE DISEASES OR INFLAMMATION | LIGAND PHARMACUETICALS INCORPORATED (US) | 2008-01-24 | — | — | WO | disclosed |