Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.67 |
| ▸ | CNR1 | P21554 | 1/20 | 0.66 |
| ▸ | CNR2 | P34972 | 1/20 | 0.66 |
| ▸ | NAMPT | P43490 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 5/20 | 0.64 |
| ▸ | NPC1 | O15118 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.59 |
| ▸ | HPGDS | O60760 | 1/20 | 0.59 |
| ▸ | FAAH | O00519 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14306236 | 0.98 | MAPT (0.69) | KMT2AMAPTEPHX2CNR1CNR2 | |
| SCHEMBL4559682 | 0.95 | MAPT (0.73) | KMT2AMAPTEPHX2CNR1CNR2 | |
| SCHEMBL2097739 | 0.86 | MAPT (0.59) | KMT2AMAPTEPHX2CNR1CNR2 | |
| SCHEMBL10253402 | 0.86 | CNR2 (0.88) | KMT2AMAPTEPHX2CNR1CNR2 | |
| SCHEMBL3072567 | 0.86 | MAPT (0.59) | KMT2AMAPTEPHX2CNR1CNR2 | |
| SCHEMBL6764534 | 0.84 | NAMPT (0.61) | MAPTEPHX2CNR1CNR2NAMPT | |
| SCHEMBL655599 | 0.84 | POLB (0.63) | MAPTCNR1CNR2NAMPTTRPV1 | |
| SCHEMBL28363944 | 0.84 | SMN1; SMN2 (0.70) | KMT2AMAPTEPHX2CNR1CNR2 | |
| SCHEMBL15134839 | 0.84 | EPHX2 (0.69) | KMT2AMAPTEPHX2CNR1CNR2 | |
| SCHEMBL10253447 | 0.84 | CNR2 (0.78) | MAPTEPHX2CNR1CNR2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12403139-B2 | Methods and compositions for prevention and treatment of cardiac hypertrophy | UNIVERSITY OF HAWAII (US) | 2025-09-02 | — | — | US | disclosed |
| EP-4400172-A2 | PIPERIDIN-4-YL AZETIDINE DERIVATIVES AS JAK1 INHIBITORS | Incyte Holdings Corporation (US) | 2024-07-17 | — | — | EP | disclosed |
| US-20240189303-A1 | METHODS AND COMPOSITIONS FOR PREVENTION AND TREATMENT OF CARDIAC HYPERTROPHY | UNIVERSITY OF HAWAII | 2024-06-13 | — | — | US | disclosed |
| WO-2023229378-A1 | HETEROCYCLIC COMPOUND AS DIACYLGLYCEROL KINASE INHIBITOR AND USE THEREOF | 주식회사 엘지화학 | 2023-11-30 | — | — | WO | disclosed |
| EP-4269394-A1 | BENZOTHIAZOLE AND BENZIMIDAZOLE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT | Korea Research Institute of Chemical Technology (KR) | 2023-11-01 | — | — | EP | disclosed |
| CN-116829542-A | Benzothiazole and benzimidazole derivatives, pharmaceutically acceptable salts, preparation method thereof and pharmaceutical composition containing same as active ingredient | 韩国化学研究院 | 2023-09-29 | — | — | CN | disclosed |
| EP-1569646-A2 | PIPERIDINE DERIVATIVES AS CCR5 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-09-07 | — | — | EP | disclosed |
| WO-2004054974-A2 | PIPERIDINE DERIVATIVES AS CCR5 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-07-01 | — | — | WO | disclosed |