Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.42 |
| ▸ | BCHE | P06276 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14318665 | 0.91 | LTA4H (0.43) | CHRM2BCHEACHECHRM1LTA4H | |
| SCHEMBL14318657 | 0.80 | DPP7 (0.43) | CHRM2BCHEACHECHRM1DPP8 | |
| SCHEMBL14307661 | 0.78 | DPP7 (0.44) | CHRM2BCHEACHECHRM1DPP7 | |
| SCHEMBL29953487 | 0.75 | CHRM2 (0.48) | CHRM2BCHEACHECHRM1APP | |
| SCHEMBL2118773 | 0.75 | LIPG (0.44) | CHRM2BCHEACHECHRM1 | |
| SCHEMBL14282727 | 0.73 | F2 (0.40) | — | |
| SCHEMBL2119569 | 0.72 | CARM1 (0.53) | CHRM2 | |
| SCHEMBL4602597 | 0.71 | LTA4H (0.39) | CHRM2CHRM1LTA4H | |
| SCHEMBL4602594 | 0.71 | LTA4H (0.39) | CHRM2CHRM1LTA4H | |
| SCHEMBL14753645 | 0.71 | LIPG (0.47) | CHRM2BCHEACHECHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7316999-B2 | Glucose dependent release of insulin from glucose sensing insulin derivatives | NOVO NORDISK A/S (DK) | 2008-01-08 | — | — | US | disclosed |