Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 8/20 | 0.45 |
| ▸ | CNR1 | P21554 | 4/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14308417 | 0.90 | CNR2 (0.49) | CYP2C19CNR2ESR1ESR2NR1H2 | |
| SCHEMBL9148067 | 0.90 | ESR1 (0.50) | CYP2C19ESR1ESR2MEN1RAB9A | |
| SCHEMBL10942182 | 0.90 | CNR2 (0.52) | CNR2ESR1ESR2NR1H2NR1H3 | |
| SCHEMBL11107077 | 0.90 | TSHR (0.47) | CYP2C19CNR2CNR1MEN1KMT2A | |
| SCHEMBL13778795 | 0.89 | CYP2C19 (0.47) | CYP2C19CNR2CNR1NR1H2NR1H3 | |
| SCHEMBL13778796 | 0.89 | CNR2 (0.40) | CYP2C19CNR2CNR1DHFRMEN1 | |
| SCHEMBL13778806 | 0.88 | CYP2C19 (0.61) | CYP2C19CNR2CNR1NR1H2NR1H3 | |
| SCHEMBL9718481 | 0.85 | CNR2 (0.47) | CNR2ESR1ESR2NR1H2NR1H3 | |
| SCHEMBL12342193 | 0.85 | CYP2C19 (0.50) | CYP2C19CNR2CNR1NR1H2NR1H3 | |
| SCHEMBL5494992 | 0.82 | ALDH1A1 (0.54) | CYP2C19CNR2NR1H2NR1H3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7314693-B2 | Electrophotographic photoconductor, electrophotographic process, electrophotographic apparatus, and process cartridge | RICOH COMPANY, LTD. (JP) | 2008-01-01 | — | — | US | disclosed |