Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10942182 | 0.92 | CNR2 (0.52) | CNR2TSHRNR1H2NR1H3MEN1 | |
| SCHEMBL14308415 | 0.90 | CYP2C19 (0.46) | CNR2TSHRNR1H2NR1H3MEN1 | |
| SCHEMBL5494992 | 0.88 | ALDH1A1 (0.54) | CNR2TSHRNR1H2NR1H3MEN1 | |
| SCHEMBL13993314 | 0.88 | ESR1 (0.52) | TSHRMEN1RAB9AKMT2AALDH1A1 | |
| SCHEMBL9718481 | 0.87 | CNR2 (0.47) | CNR2TSHRNR1H2NR1H3MEN1 | |
| SCHEMBL13594999 | 0.86 | TSHR (0.61) | CNR2TSHRMEN1RAB9AKMT2A | |
| SCHEMBL13778806 | 0.81 | CYP2C19 (0.61) | CNR2TSHRNR1H2NR1H3KMT2A | |
| SCHEMBL11107077 | 0.81 | TSHR (0.47) | CNR2TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL25754057 | 0.81 | ESR1 (0.50) | MEN1KMT2AALDH1A1TDP1CYP3A4 | |
| SCHEMBL13778796 | 0.81 | CNR2 (0.40) | CNR2TSHRMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7314693-B2 | Electrophotographic photoconductor, electrophotographic process, electrophotographic apparatus, and process cartridge | RICOH COMPANY, LTD. (JP) | 2008-01-01 | — | — | US | disclosed |