Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.41 |
| ▸ | CNR2 | P34972 | 11/20 | 0.41 |
| ▸ | CNR1 | P21554 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14283648 | 0.91 | CYP2C19 (0.66) | CYP2C19NR1H2NR1H3CNR2CNR1 | |
| SCHEMBL13778806 | 0.83 | CYP2C19 (0.61) | CYP2C19NR1H2NR1H3CNR2CNR1 | |
| SCHEMBL10633353 | 0.82 | CYP2C19 (0.50) | CYP2C19CNR2CNR1NPSR1 | |
| SCHEMBL13308481 | 0.80 | SLC6A2 (0.44) | CYP2C19CNR2CNR1NPSR1 | |
| SCHEMBL14283625 | 0.79 | CNR2 (0.48) | CYP2C19CNR2CNR1TSHR | |
| SCHEMBL12346035 | 0.79 | SLC6A2 (0.46) | CYP2C19CNR2CNR1NPSR1 | |
| SCHEMBL15159187 | 0.79 | CYP2C19 (0.89) | CYP2C19NR1H2NR1H3CNR2CNR1 | |
| SCHEMBL14283606 | 0.78 | CNR2 (0.47) | CYP2C19CNR2CNR1TSHR | |
| SCHEMBL23251188 | 0.77 | SLC6A2 (0.44) | CYP2C19CNR2CNR1NPSR1 | |
| SCHEMBL14308415 | 0.75 | CYP2C19 (0.46) | CYP2C19NR1H2NR1H3CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7314693-B2 | Electrophotographic photoconductor, electrophotographic process, electrophotographic apparatus, and process cartridge | RICOH COMPANY, LTD. (JP) | 2008-01-01 | — | — | US | disclosed |