Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.47 |
| ▸ | APAF1 | O14727 | 2/20 | 0.42 |
| ▸ | NSD2 | O96028 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 2/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | NNMT | P40261 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29659749 | 1.00 | IKBKB (0.47) | IKBKBAPAF1NSD2CASP3SENP8 | |
| SCHEMBL14284230 | 0.84 | LMNA (0.44) | IKBKBAPAF1NSD2CASP3SENP8 | |
| SCHEMBL753212 | 0.84 | CA12 (0.44) | APAF1NSD2CASP3SENP8SENP7 | |
| SCHEMBL21855442 | 0.82 | IKBKB (0.54) | IKBKBAPAF1NSD2CASP3SENP8 | |
| SCHEMBL27339338 | 0.82 | IKBKB (0.47) | IKBKBAPAF1NSD2CASP3SENP8 | |
| Hydrochloric Acid SCHEMBL5583653 | 0.82 | CA12 (0.43) | APAF1NSD2CASP3SENP8SENP7 | |
| SCHEMBL28310205 | 0.82 | KDM4E (0.38) | IKBKBAPAF1NSD2CASP3SENP8 | |
| SCHEMBL18824893 | 0.82 | L3MBTL1 (0.46) | APAF1NSD2CASP3SENP8SENP7 | |
| SCHEMBL17785403 | 0.81 | IKBKB (0.46) | IKBKBAPAF1NSD2CASP3SENP8 | |
| Hydrochloric Acid SCHEMBL5008136 | 0.81 | IKBKB (0.46) | IKBKBAPAF1NSD2CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976622-B1 | MICROBIOCIDAL DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2023-10-18 | — | — | EP | disclosed |
| WO-2020239854-A1 | MICROBIOCIDAL DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2020-12-03 | — | — | WO | disclosed |
| EP-3240419-B1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2020-05-06 | — | — | EP | disclosed |
| WO-2017116939-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2017-07-06 | — | — | WO | disclosed |
| EP-1516874-B1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2015-08-19 | — | — | EP | disclosed |
| US-RE39991-E1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2008-01-01 | — | — | US | disclosed |
| CN-1261432-C | Reductive cleavage of the exocyclic ester of UK-2A or its derivatives and products formed therefrom | DOW AGROSCIENCES LLC (US) | 2006-06-28 | — | — | CN | disclosed |
| CN-1549815-A | Reductive cleavage of the exocyclic ester of UK-2A or its derivatives and products formed therefrom | �ݶ�ũ������˾ | 2004-11-24 | — | — | CN | disclosed |