Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | GPR3 | P46089 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | PARP1 | P09874 | 3/20 | 0.58 |
| ▸ | AURKA | O14965 | 2/20 | 0.58 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.57 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.57 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.57 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.57 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.57 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.57 |
| ▸ | GABRP | O00591 | 2/20 | 0.57 |
| ▸ | GABRD | O14764 | 2/20 | 0.57 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.57 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.57 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.57 |
| ▸ | GABRE | P78334 | 2/20 | 0.57 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.57 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.57 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbazole SCHEMBL28956846 | 1.00 | ALDH1A1 (0.58) | ALDH1A1GPR3HSD17B10PARP1AURKA | |
| SCHEMBL29559082 | 0.98 | PARP1 (0.60) | ALDH1A1GPR3HSD17B10PARP1AURKA | |
| SCHEMBL29410201 | 0.98 | PARP1 (0.60) | ALDH1A1GPR3HSD17B10PARP1AURKA | |
| SCHEMBL9145 | 0.98 | PARP1 (0.60) | ALDH1A1GPR3HSD17B10PARP1AURKA | |
| SCHEMBL28982242 | 0.96 | PARP1 (0.58) | ALDH1A1GPR3HSD17B10PARP1AURKA | |
| Hydrochloric Acid SCHEMBL2770160 | 0.96 | PARP1 (0.58) | ALDH1A1GPR3HSD17B10PARP1AURKA | |
| Formaldehyde SCHEMBL28560487 | 0.92 | PARP1 (0.59) | ALDH1A1GPR3HSD17B10PARP1AURKA | |
| SCHEMBL27174122 | 0.91 | PARP1 (0.56) | ALDH1A1GPR3HSD17B10PARP1AURKA | |
| Norharmane SCHEMBL6646064 | 0.89 | CHUK (0.77) | ALDH1A1PARP1AURKAGABRA1GABRG2 | |
| SCHEMBL18597137 | 0.88 | MAPT (0.53) | ALDH1A1GPR3HSD17B10PARP1AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112028912-B | Novel boron-containing organic electroluminescent material and application thereof | 北京鼎材科技有限公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-114933591-B | Pyridine derivative and application thereof | 北京鼎材科技有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-110407810-B | Organic electroluminescent material and application thereof | 北京鼎材科技有限公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-112614952-B | Organic light-emitting device and display device | 昆山国显光电有限公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-114933591-A | Pyridine derivatives and use thereof | 北京鼎材科技有限公司 | 2022-08-23 | — | — | CN | disclosed |
| CN-110452239-B | Nitrogen-containing heterocyclic compound, application thereof and organic electroluminescent device | 北京鼎材科技有限公司 | 2022-03-29 | — | — | CN | disclosed |
| CN-112614952-A | Organic electroluminescent device and display device | 昆山国显光电有限公司 | 2021-04-06 | — | — | CN | disclosed |
| CN-112028912-A | Novel boron-containing organic electroluminescent material and application thereof | 北京鼎材科技有限公司 | 2020-12-04 | — | — | CN | disclosed |
| CN-110452239-A | Nitrogen-containing heterocycle compound and its application and organic electroluminescence device | BEIJING ETERNAL MAT TECH CO LTD | 2019-11-15 | — | — | CN | disclosed |
| CN-110407810-A | Organic electroluminescent material and application thereof | BEIJING ETERNAL MAT TECH CO LTD | 2019-11-05 | — | — | CN | disclosed |
| US-8815840-B2 | Carbazole and carboline kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-08-26 | — | — | US | disclosed |
| EP-2370407-B1 | CARBAZOLE AND CARBOLINE KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2014-06-18 | — | — | EP | disclosed |
| US-20120058988-A1 | CARBAZOLE AND CARBOLINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2012-03-08 | — | — | US | disclosed |
| EP-2370407-A1 | CARBAZOLE AND CARBOLINE KINASE INHIBITORS | Bristol-Myers Squibb Company (US) | 2011-10-05 | — | — | EP | disclosed |
| WO-2010080474-A1 | CARBAZOLE AND CARBOLINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-07-15 | — | — | WO | disclosed |
| JP-2004318049-A | PHOTOSENSITIVE COMPOSITION AND NOVEL COMPOUND USING THE SAME | FUJI PHOTO FILM CO LTD | 2004-11-11 | — | — | JP | disclosed |
| JP-2004319439-A | DYE-SENSITIZED SOLAR CELL AND ITS MANUFACTURING METHOD | SHARP CORP | 2004-11-11 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058988-A1 | CARBAZOLE AND CARBOLINE KINASE INHIBITORS | JAK2, JAK1, JAK3 | ALDH1A1 1464/4885GPR3 1326/4885HSD17B10 2440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.