SCHEMBL9145

SCHEMBL9145

c1ccc2c(c1)[nH]c1ncccc12

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 4/20 0.60
AURKA O14965 2/20 0.60
ALDH1A1 P00352 3/20 0.54
HSD17B10 Q99714 2/20 0.54
GPR3 P46089 1/20 0.54
GABRA1 P14867 3/20 0.54
GABRG2 P18507 3/20 0.54
GABRB3 P28472 3/20 0.54
GABRA5 P31644 3/20 0.54
GABRA3 P34903 3/20 0.54
GABRA2 P47869 3/20 0.54
TDO2 P48775 3/20 0.53
KDM4E B2RXH2 2/20 0.53
GABRP O00591 2/20 0.53
GABRD O14764 2/20 0.53
HPGD P15428 2/20 0.53
GABRB1 P18505 2/20 0.53
MAOA P21397 2/20 0.53
GABRB2 P47870 2/20 0.53
GABRA4 P48169 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29410201 1.00 PARP1 (0.60) PARP1AURKAALDH1A1HSD17B10GPR3
SCHEMBL29559082 1.00 PARP1 (0.60) PARP1AURKAALDH1A1HSD17B10GPR3
Carbazole SCHEMBL143086 0.98 ALDH1A1 (0.58) PARP1AURKAALDH1A1HSD17B10GPR3
Carbazole SCHEMBL28956846 0.98 ALDH1A1 (0.58) PARP1AURKAALDH1A1HSD17B10GPR3
Hydrochloric Acid SCHEMBL2770160 0.98 PARP1 (0.58) PARP1AURKAALDH1A1HSD17B10GPR3
SCHEMBL28982242 0.98 PARP1 (0.58) PARP1AURKAALDH1A1HSD17B10GPR3
Formaldehyde SCHEMBL28560487 0.94 PARP1 (0.59) PARP1AURKAALDH1A1HSD17B10GPR3
Guanidine SCHEMBL6505156 0.89 PARP1 (0.50) PARP1AURKAALDH1A1HSD17B10GPR3
SCHEMBL27174122 0.89 PARP1 (0.56) PARP1AURKAALDH1A1HSD17B10GPR3
Norharmane SCHEMBL6646064 0.88 CHUK (0.77) PARP1AURKAALDH1A1GABRA1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 35508 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260150490-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, AND ELECTRONIC APPARATUS INCLUDING ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2026-05-28 US claimed
US-20260150489-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2026-05-28 US claimed
US-20260150572-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2026-05-28 US claimed
CN-122080075-A Organometallic compound, organic light-emitting device including the same, and electronic apparatus including the organic light-emitting device 2026-05-26 CN claimed
CN-122080076-A Organometallic compound, organic light-emitting device including the same, and electronic apparatus including the organic light-emitting device 2026-05-26 CN claimed
CN-122071492-A Organic electroluminescent material and device 环球展览公司 2026-05-22 CN claimed
CN-122071495-A Organic electroluminescent material and device 环球展览公司 2026-05-22 CN claimed
CN-122071496-A Organic electroluminescent material and device 环球展览公司 2026-05-22 CN claimed
CN-122071498-A Organic electroluminescent material and device 环球展览公司 2026-05-22 CN claimed
CN-122071494-A Organic electroluminescent material and device 环球展览公司 2026-05-22 CN claimed
EP-0347980-A1 8,9-Annelated beta-carbolines and 8,9-anelated-3,4-dihydro-beta-carbolines DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1989-12-27 EP claimed
EP-0320075-A1 8,9-Annelated-beta-carbolines and 8,9-annelated-3,4-dihydro-beta-carbolines DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1989-06-14 EP claimed
WO-1989001472-A1 MELATONIN ANALOGUES NELSON RESEARCH & DEVELOPMENT CO. (US) 1989-02-23 WO claimed
EP-0300541-A1 8,9-anellated-1,2,3,4-tetrahydro-beta-carboline derivatives DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1989-01-25 EP claimed
EP-0222474-A1 Gamma-carbolines AMERICAN HOME PRODUCTS CORPORATION (US) 1987-05-20 EP claimed
EP-0039804-B1 CYCLIC AMIDES USV PHARMACEUTICAL CORPORATION (US) 1986-08-20 EP claimed
EP-0148660-A1 Beta-carboline derivatives, process for their preparation and medicaments containing them Etablissement Public dit: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1985-07-17 EP claimed
EP-0011059-B1 PROCESS FOR THE PREPARATION OF (+,-) VINCADIFFORMINE AND OTHER RELATED PENTACYCLIC DERIVATIVES OMNICHEM Société anonyme (BE) 1983-08-31 EP claimed
US-4220774-A Vincadifformine synthesis process OMNIUM CHIMIQUE (BE) 1980-09-02 US claimed
EP-0011059-A1 Process for the preparation of (+,-) vincadifformine and other related pentacyclic derivatives OMNICHEM Société anonyme (BE) 1980-05-14 EP claimed