Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 5/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.33 |
| ▸ | F2 | P00734 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14313050 | 0.92 | HPGDS (0.57) | HPGDSL3MBTL1ALDH1A1KDM4EGLA | |
| SCHEMBL14312635 | 0.92 | HPGDS (0.44) | HPGDSCNR1 | |
| SCHEMBL14313181 | 0.89 | HPGDS (0.60) | HPGDSL3MBTL1ALDH1A1KDM4EGLA | |
| SCHEMBL14312968 | 0.88 | HPGDS (0.40) | HPGDSCNR1 | |
| SCHEMBL12083895 | 0.87 | HPGDS (0.73) | HPGDSGLAKLKB1F2MEN1 | |
| SCHEMBL14313003 | 0.86 | HPGDS (0.39) | HPGDS | |
| SCHEMBL14312953 | 0.86 | HPGDS (0.73) | HPGDSL3MBTL1ALDH1A1KDM4EKLKB1 | |
| SCHEMBL14313196 | 0.83 | HPGDS (0.60) | HPGDSL3MBTL1ALDH1A1KDM4EGLA | |
| SCHEMBL14313161 | 0.82 | HPGDS (0.48) | HPGDSL3MBTL1ALDH1A1KDM4EF2 | |
| SCHEMBL14313346 | 0.80 | HPGDS (0.41) | HPGDSCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142516-B1 | PYRIMIDINE HYDRAZIDE COMPOUNDS AS PGDS INHIBITORS | SANOFI SA (FR) | 2012-12-26 | — | — | EP | claimed |