Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 11/20 | 0.57 |
| ▸ | PRKAA1 | Q13131 | 11/20 | 0.57 |
| ▸ | PRKAA2 | P54646 | 10/20 | 0.57 |
| ▸ | PDGFRB | P09619 | 7/20 | 0.57 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.57 |
| ▸ | EGFR | P00533 | 2/20 | 0.57 |
| ▸ | KIT | P10721 | 2/20 | 0.57 |
| ▸ | NEK2 | P51955 | 2/20 | 0.57 |
| ▸ | PLK4 | O00444 | 2/20 | 0.57 |
| ▸ | DCLK1 | O15075 | 2/20 | 0.57 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.57 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.57 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.57 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.57 |
| ▸ | INSR | P06213 | 2/20 | 0.57 |
| ▸ | LCK | P06239 | 2/20 | 0.57 |
| ▸ | CSF1R | P07333 | 2/20 | 0.57 |
| ▸ | RET | P07949 | 2/20 | 0.57 |
| ▸ | SRC | P12931 | 2/20 | 0.57 |
| ▸ | PHKG2 | P15735 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL148704 | 0.87 | KDR (0.62) | KDRPRKAA1PRKAA2PDGFRBFGFR1 | |
| SCHEMBL149330 | 0.87 | KDR (0.56) | KDRPRKAA1PRKAA2PDGFRBFGFR1 | |
| SCHEMBL148478 | 0.87 | KDR (0.61) | KDRPRKAA1PRKAA2PDGFRBFGFR1 | |
| SCHEMBL144118 | 0.86 | KDR (0.61) | KDRPRKAA1PRKAA2PDGFRBFGFR1 | |
| SCHEMBL144378 | 0.85 | KDR (0.66) | KDRPRKAA1PRKAA2PDGFRBFGFR1 | |
| SCHEMBL145924 | 0.85 | KDR (0.59) | KDRPRKAA1PRKAA2PDGFRBFGFR1 | |
| SCHEMBL143827 | 0.85 | PRKAA1 (0.59) | KDRPRKAA1PRKAA2PDGFRBFGFR1 | |
| SCHEMBL143534 | 0.84 | KDR (0.72) | KDRPRKAA1PRKAA2PDGFRBFGFR1 | |
| SCHEMBL143148 | 0.84 | PDGFRB (0.56) | KDRPRKAA1PRKAA2PDGFRBFGFR1 | |
| SCHEMBL144183 | 0.84 | KDR (0.58) | KDRPRKAA1PRKAA2PDGFRBFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120059047-A1 | DIFFERENTIATION MODULATING AGENTS AND USES THEREFOR | VERVA PHARMACEUTICALS PTY LTD (AU) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059047-A1 | DIFFERENTIATION MODULATING AGENTS AND USES THEREFOR | FGF1, FABP4, FGF2 | KDR 1077/4885PRKAA1 322/4885PRKAA2 396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.