Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1000974 | 0.76 | MAOA (0.51) | MAOAMAOB | |
| SCHEMBL19710068 | 0.74 | MAOA (0.43) | MAOAMAOB | |
| SCHEMBL23396320 | 0.73 | TDP1 (0.35) | MAOAMAOB | |
| SCHEMBL16082149 | 0.73 | CA12 (0.47) | MAOAMAOB | |
| SCHEMBL12180827 | 0.71 | ALDH1A1 (0.33) | MAOAMAOB | |
| SCHEMBL25940885 | 0.70 | TDP1 (0.31) | — | |
| SCHEMBL19374626 | 0.68 | KDM4C (0.35) | — | |
| SCHEMBL17690249 | 0.68 | EGLN1 (0.37) | MAOAMAOB | |
| SCHEMBL1926396 | 0.67 | MAOA (0.39) | MAOAMAOB | |
| SCHEMBL11888650 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008011557-A2 | HETEROARYL INHIBITORS OF RHO KINASE | BORCHARDT ALLEN J (US) | 2008-01-24 | — | — | WO | disclosed |