Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 4/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.68 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.68 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.68 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.67 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.66 |
| ▸ | MAOB | P27338 | 1/20 | 0.65 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.59 |
| ▸ | KRAS | P01116 | 2/20 | 0.59 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15807308 | 0.91 | ALDH1A1 (0.67) | ABCB1MAPTALDH1A1LMNAHTT | |
| SCHEMBL29803074 | 0.91 | MAPT (0.79) | ABCB1MAPTALDH1A1LMNAHTT | |
| SCHEMBL21643392 | 0.91 | MAPT (0.79) | ABCB1MAPTALDH1A1LMNAHTT | |
| SCHEMBL14318108 | 0.88 | MAPT (0.79) | ABCB1MAPTALDH1A1LMNAHTT | |
| SCHEMBL15807747 | 0.86 | KRAS (0.77) | ABCB1MAPTALDH1A1LMNATNFRSF1A | |
| SCHEMBL14306012 | 0.85 | MAPT (0.76) | MAPTALDH1A1LMNAHTTTXNRD1 | |
| SCHEMBL15807401 | 0.85 | TXNRD1 (0.64) | ABCB1MAPTALDH1A1LMNAHTT | |
| SCHEMBL14306019 | 0.84 | MAPT (0.91) | MAPTALDH1A1LMNAHTTTXNRD1 | |
| SCHEMBL15795550 | 0.84 | TXNRD1 (0.84) | ABCB1MAPTALDH1A1LMNAHTT | |
| SCHEMBL15795549 | 0.84 | TXNRD1 (0.84) | ABCB1MAPTALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3333153-A1 | NUCLEAR RECEPTOR MODULATORS AND THEIR USE FOR THE TREATMENT AND PREVENTION OF CANCER | The U.S.A. as represented by the Secretary, Department of Health and Human Services (US) | 2018-06-13 | — | — | EP | disclosed |
| US-20140171503-A1 | NUCLEAR RECEPTOR MODULATORS AND THEIR USE FOR THE TREATMENT AND PREVENTION OF CANCER | HUMAN SERVICES (US) | 2014-06-19 | — | — | US | disclosed |
| WO-2012174436-A1 | NUCLEAR RECEPTOR MODULATORS AND THEIR USE FOR THE TREATMENT AND PREVENTION OF CANCER | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2012-12-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140171503-A1 | NUCLEAR RECEPTOR MODULATORS AND THEIR USE FOR THE TREATMENT AND PREVENTION OF CANCER | AR, NCOA1, NR5A1 | ABCB1 934/4885MAPT 4183/4885ALDH1A1 902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.