Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14325885 | 0.95 | SRC (0.37) | SRCKDM4EL3MBTL1ALDH1A1ADRA2A | |
| SCHEMBL7870086 | 0.88 | SRC (0.37) | SRCKDM4EL3MBTL1ALDH1A1ADRA2A | |
| SCHEMBL14318539 | 0.77 | MAPT (0.43) | SRCALDH1A1MAPTMAOAMAOB | |
| SCHEMBL14306425 | 0.76 | RAPGEF4 (0.44) | SRCL3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL14318538 | 0.76 | ADORA1 (0.43) | KDM4EL3MBTL1ALDH1A1MAPTMAOA | |
| SCHEMBL14315663 | 0.75 | MAP2K1 (0.48) | SRCMAPK1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL14318544 | 0.75 | ADRA2A (0.41) | ALDH1A1ADRA2AADRA2CMAPTMAPK1 | |
| SCHEMBL14318557 | 0.74 | SRC (0.39) | SRCKDM4EL3MBTL1ALDH1A1ADRA2A | |
| SCHEMBL14325892 | 0.74 | MAPT (0.41) | SRCKDM4EL3MBTL1ALDH1A1ADRA2A | |
| SCHEMBL14315679 | 0.73 | SRC (0.43) | SRCL3MBTL1ALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937072-B2 | Substituted cyanoaniline compounds, preparation and use thereof | SINOCHEM CORPORATION (CN) | 2015-01-20 | — | — | US | disclosed |
| US-20140213598-A1 | SUBSTITUTED CYANOANILINE COMPOUNDS, PREPARATION AND USE THEREOF | SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD. (CN) | 2014-07-31 | — | — | US | disclosed |
| WO-2012171484-A1 | SUBSTITUTED CYANOANILINE COMPOUNDS, PREPARATION AND USE THEREOF | 中国中化股份有限公司 (CN) | 2012-12-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140213598-A1 | SUBSTITUTED CYANOANILINE COMPOUNDS, PREPARATION AND USE THEREOF | CROCC, MASTL, SLC7A1 | SRC 1992/4885KDM4E 2574/4885L3MBTL1 459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.