SCHEMBL14315736

SCHEMBL14315736

Cc1ccc(-n2c3ccccc3c3c2ccc2c4ccccc4n(-c4ccccc4)c23)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.53
ATM Q13315 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
MAPT P10636 2/20 0.39
HTT P42858 2/20 0.39
LMNA P02545 1/20 0.39
ALDH1A1 P00352 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38
MAPK8 P45983 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ALKBH5 Q6P6C2 1/20 0.35
FTO Q9C0B1 1/20 0.35
AKR1C4 P17516 1/20 0.35
AKR1C3 P42330 1/20 0.35
AKR1C2 P52895 1/20 0.35
AKR1C1 Q04828 1/20 0.35
PGR P06401 1/20 0.35
MAPK1 P28482 1/20 0.34
METAP2 P50579 1/20 0.34
JAK2 O60674 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15451807 1.00 KDM4E (0.53) KDM4EATML3MBTL1MAPTHTT
SCHEMBL14313942 0.97 KDM4E (0.47) KDM4EATML3MBTL1MAPTHTT
SCHEMBL20412007 0.95 KDM4E (0.47) KDM4EATML3MBTL1MAPTHTT
SCHEMBL14325134 0.93 KDM4E (0.45) KDM4EATML3MBTL1MAPTALDH1A1
SCHEMBL17245455 0.92 L3MBTL1 (0.62) KDM4EATML3MBTL1MAPTHTT
SCHEMBL10027641 0.92 L3MBTL1 (0.62) KDM4EATML3MBTL1MAPTHTT
SCHEMBL26060236 0.92 L3MBTL1 (0.62) KDM4EATML3MBTL1MAPTHTT
SCHEMBL10027526 0.92 L3MBTL1 (0.62) KDM4EATML3MBTL1MAPTHTT
SCHEMBL12691126 0.92 L3MBTL1 (0.62) KDM4EATML3MBTL1MAPTHTT
SCHEMBL31744513 0.92 L3MBTL1 (0.62) KDM4EATML3MBTL1MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230122208-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-20 US disclosed
US-11548905-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-01-10 US disclosed
US-20210111348-A1 POLYMER FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2021-04-15 US disclosed
US-20210028376-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-01-28 US disclosed
US-9627631-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-04-18 US disclosed
US-9318710-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-04-19 US disclosed
US-20160028016-A1 BORON-NITROGEN POLYAROMATIC COMPOUNDS AND THEIR USE IN OLEDS UNIVERSAL DISPLAY CORPORATION (US) 2016-01-28 US disclosed
US-20140027734-A1 BORON-NITROGEN POLYAROMATIC COMPOUNDS AND THEIR USE IN OLEDS UNIVERSAL DISPLAY CORPORATION (US) 2014-01-30 US disclosed
WO-2012171609-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2012-12-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230122208-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ZYX, SLC39A3, SOD3 KDM4E 1688/4885ATM 3316/4885L3MBTL1 155/4885
US-11548905-B2 Organic electroluminescent materials and devices ZYX, SLC39A3, SOD3 KDM4E 1688/4885ATM 3316/4885L3MBTL1 155/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.