Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14317173 | 0.93 | MAPT (0.49) | MAPTSMN1; SMN2DYRK1ACD274RAD52 | |
| SCHEMBL14246841 | 0.90 | NPSR1 (0.46) | MAPTSMN1; SMN2CD274NPSR1ALDH1A1 | |
| SCHEMBL14317872 | 0.80 | DYRK1A (0.56) | MAPTSMN1; SMN2DYRK1ACD274RAD52 | |
| SCHEMBL14317873 | 0.77 | MAPT (0.49) | MAPTSMN1; SMN2DYRK1ACD274RAD52 | |
| SCHEMBL14317875 | 0.76 | LMNA (0.51) | MAPTSMN1; SMN2DYRK1ANPSR1HPGD | |
| SCHEMBL14317874 | 0.76 | MAPT (0.48) | MAPTSMN1; SMN2DYRK1ACD274RAD52 | |
| SCHEMBL14246865 | 0.73 | DYRK1A (0.56) | MAPTSMN1; SMN2DYRK1ACD274RAD52 | |
| SCHEMBL14246744 | 0.72 | DYRK1A (0.54) | MAPTSMN1; SMN2DYRK1ACD274RAD52 | |
| SCHEMBL14246858 | 0.70 | MAPT (0.50) | MAPTSMN1; SMN2DYRK1ACD274RAD52 | |
| SCHEMBL14246721 | 0.70 | MAPT (0.49) | MAPTSMN1; SMN2DYRK1ACD274RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012174488-A2 | AGENTS AND METHODS FOR TREATING ISCHEMIC AND OTHER DISEASES | NONO, INC. (CA) | 2012-12-20 | — | — | WO | disclosed |