Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
| ▸ | CLK1 | P49759 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14325654 | 0.93 | LMNA (0.51) | LMNADYRK1ACLK1MAPTSMN1; SMN2 | |
| SCHEMBL14246970 | 0.90 | HPGD (0.55) | LMNAMAPTSMN1; SMN2TP53POLB | |
| SCHEMBL14317872 | 0.90 | DYRK1A (0.56) | LMNADYRK1AMAPTSMN1; SMN2POLB | |
| SCHEMBL14246865 | 0.83 | DYRK1A (0.56) | LMNADYRK1AMAPTSMN1; SMN2POLB | |
| SCHEMBL14317873 | 0.81 | MAPT (0.49) | LMNADYRK1AMAPTSMN1; SMN2POLB | |
| SCHEMBL14317874 | 0.80 | MAPT (0.48) | LMNADYRK1AMAPTSMN1; SMN2POLB | |
| SCHEMBL14317877 | 0.80 | NPSR1 (0.49) | LMNADYRK1AMAPTSMN1; SMN2TP53 | |
| SCHEMBL14246858 | 0.77 | MAPT (0.50) | LMNADYRK1AMAPTSMN1; SMN2POLB | |
| SCHEMBL14317871 | 0.76 | MAPT (0.49) | LMNADYRK1AMAPTSMN1; SMN2TP53 | |
| SCHEMBL14317880 | 0.76 | SMN1; SMN2 (0.48) | LMNADYRK1AMAPTSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012174488-A2 | AGENTS AND METHODS FOR TREATING ISCHEMIC AND OTHER DISEASES | NONO, INC. (CA) | 2012-12-20 | — | — | WO | disclosed |