Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 9/20 | 0.36 |
| ▸ | RARB | P10826 | 3/20 | 0.36 |
| ▸ | RARG | P13631 | 3/20 | 0.36 |
| ▸ | RXRB | P28702 | 2/20 | 0.36 |
| ▸ | RXRG | P48443 | 2/20 | 0.36 |
| ▸ | RARA | P10276 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14365749 | 0.86 | CYP2C8 (0.35) | CYP2C8CYP2C9RXRARARBRARG | |
| SCHEMBL2606548 | 0.82 | PDK2 (0.43) | PDK2CYP2C8CYP2C9CNR2RXRA | |
| SCHEMBL25011572 | 0.74 | PDK2 (0.62) | PDK2CYP2C8CYP2C9CNR2RXRA | |
| SCHEMBL2606549 | 0.73 | PDK2 (0.43) | PDK2CYP2C8CYP2C9CNR2RXRA | |
| SCHEMBL13045515 | 0.73 | PDK2 (0.52) | PDK2RXRARARBRARGRXRB | |
| SCHEMBL353237 | 0.72 | CYP2C8 (0.40) | CYP2C8CYP2C9RXRARARBRARG | |
| SCHEMBL14096707 | 0.72 | PDK2 (0.52) | PDK2CYP2C8CYP2C9CNR2RXRA | |
| SCHEMBL14073311 | 0.72 | PDK2 (0.49) | PDK2RXRARARBRARGRXRB | |
| SCHEMBL1638586 | 0.71 | CYP2C8 (0.43) | PDK2CYP2C8CYP2C9CNR2RXRA | |
| SCHEMBL13624457 | 0.71 | CNR2 (0.43) | PDK2CNR2ATMTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008006449-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2008-01-17 | — | — | WO | disclosed |