SCHEMBL1638586

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10227419	0.92	CYP2C8 (0.46)	CYP2C8MAPK13MAPK12MAPK11MAPK14
	SCHEMBL29307110	0.83	PDK2 (0.48)	CYP2C8MAPK13MAPK12MAPK11MAPK14
	SCHEMBL13045515	0.82	PDK2 (0.52)	PDK2RARBRARGRXRA
	SCHEMBL2381120	0.82	CDC25B (0.55)	CYP2C8PDK2CYP2C9CDC25BCDC25A
	SCHEMBL27438715	0.80	PDK2 (0.55)	PDK2RARBRARGRXRAMEN1
	SCHEMBL14073397	0.80	CNR2 (0.45)	MEN1KMT2AMAPTCDC25BCNR2
	SCHEMBL21025032	0.79	ALDH1A1 (0.47)	MAPK13MAPK12MAPK11MAPK14PDK2
	SCHEMBL9886708	0.79	PDK2 (0.55)	PDK2RARBRARGRXRA
	SCHEMBL14073311	0.78	PDK2 (0.49)	PDK2RARBRARGRXRA
	SCHEMBL25011572	0.78	PDK2 (0.62)	CYP2C8PDK2RARBRARGRXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.