Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
| ▸ | PLK4 | O00444 | 2/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.39 |
| ▸ | PRKCG | P05129 | 2/20 | 0.39 |
| ▸ | PIM1 | P11309 | 2/20 | 0.39 |
| ▸ | PHKG2 | P15735 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | AXL | P30530 | 2/20 | 0.39 |
| ▸ | AKT1 | P31749 | 2/20 | 0.39 |
| ▸ | AKT2 | P31751 | 2/20 | 0.39 |
| ▸ | SYK | P43405 | 2/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.39 |
| ▸ | CLK2 | P49760 | 2/20 | 0.39 |
| ▸ | GSK3A | P49840 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10880209 | 0.78 | CYP1A2 (0.41) | CYP2C9CYP1A2CYP2C19ALDH1A1TSHR | |
| SCHEMBL3889410 | 0.74 | KCNN4 (0.44) | CYP2C9CYP1A2CYP2C19ALDH1A1TSHR | |
| SCHEMBL8793851 | 0.74 | ALDH1A1 (0.44) | CYP2C9CYP1A2CYP2C19ALDH1A1KCNN4 | |
| SCHEMBL8793845 | 0.74 | ALDH1A1 (0.44) | CYP2C9CYP1A2CYP2C19ALDH1A1KCNN4 | |
| SCHEMBL26839406 | 0.72 | CYP2C9 (0.43) | CYP2C9CYP1A2CYP2C19ALDH1A1TSHR | |
| SCHEMBL13894152 | 0.72 | CYP2C9 (0.43) | CYP2C9CYP1A2CYP2C19ALDH1A1TSHR | |
| Benzylic Acid SCHEMBL7066 | 0.72 | CYP2C9 (0.74) | CYP2C9CYP1A2CYP2C19ALDH1A1TSHR | |
| SCHEMBL9056652 | 0.72 | CYP2C9 (0.54) | CYP2C9CYP1A2CYP2C19KCNN4PLK4 | |
| SCHEMBL8187278 | 0.71 | KCNN4 (0.58) | CYP2C9CYP1A2CYP2C19ALDH1A1TSHR | |
| SCHEMBL10657920 | 0.71 | CYP1A2 (0.44) | CYP2C9CYP1A2CYP2C19ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300244-B1 | TYRE AND CROSSLINKABLE ELASTOMERIC COMPOSITION COMPRISING AN OXETANE DERIVATIVE AND A CARBOXYLIC ACID | PIRELLI (IT) | 2011-12-14 | — | — | EP | claimed |
| EP-2300244-A1 | TYRE AND CROSSLINKABLE ELASTOMERIC COMPOSITION COMPRISING AN OXETANE DERIVATIVE AND A CARBOXYLIC ACID | Pirelli Tyre S.P.A. (IT) | 2011-03-30 | — | — | EP | claimed |
| WO-2010000294-A1 | TYRE AND CROSSLINKABLE ELASTOMERIC COMPOSITION COMPRISING AN OXETANE DERIVATIVE AND A CARBOXYLIC ACID | PIRELLI TYRE S.P.A. (IT) | 2010-01-07 | — | — | WO | claimed |
| EP-2300244-B1 | TYRE AND CROSSLINKABLE ELASTOMERIC COMPOSITION COMPRISING AN OXETANE DERIVATIVE AND A CARBOXYLIC ACID | PIRELLI (IT) | 2011-12-14 | — | — | EP | disclosed |
| US-20110177255-A1 | METHOD FOR PRODUCING AN ALDEHYDE CONTAINING COATING | UNIVERSITY OF DURHAM (GB) | 2011-07-21 | — | — | US | disclosed |
| EP-2300244-A1 | TYRE AND CROSSLINKABLE ELASTOMERIC COMPOSITION COMPRISING AN OXETANE DERIVATIVE AND A CARBOXYLIC ACID | Pirelli Tyre S.P.A. (IT) | 2011-03-30 | — | — | EP | disclosed |
| WO-2010000294-A1 | TYRE AND CROSSLINKABLE ELASTOMERIC COMPOSITION COMPRISING AN OXETANE DERIVATIVE AND A CARBOXYLIC ACID | PIRELLI TYRE S.P.A. (IT) | 2010-01-07 | — | — | WO | disclosed |
| EP-1866103-B1 | A METHOD FOR PRODUCING AN ALDEHYDE CONTAINING COATING | SURFACE INNOVATIONS LTD (GB) | 2009-07-22 | — | — | EP | disclosed |
| EP-1866103-A1 | A METHOD FOR PRODUCING AN ALDEHYDE CONTAINING COATING | UNIVERSITY OF DURHAM (GB) | 2007-12-19 | — | — | EP | disclosed |
| WO-2006100480-A1 | A METHOD FOR PRODUCING AN ALDEHYDE CONTAINING COATING | UNIVERSITY OF DURHAM (GB) | 2006-09-28 | — | — | WO | disclosed |