Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8793851 | 1.00 | ALDH1A1 (0.44) | ALDH1A1ALOX15ESR1ESR2CYP3A4 | |
| SCHEMBL28561127 | 0.81 | ALDH1A1 (0.41) | ALDH1A1ALOX15ESR1ESR2CYP3A4 | |
| SCHEMBL1537246 | 0.77 | HDAC3 (0.50) | ALDH1A1ALOX15ESR1ESR2CYP3A4 | |
| SCHEMBL28097822 | 0.77 | ALDH1A1 (0.46) | ALDH1A1ALOX15ESR1ESR2CYP3A4 | |
| SCHEMBL3360360 | 0.77 | MAPT (0.54) | ALDH1A1ALOX15ESR1ESR2CYP3A4 | |
| SCHEMBL197251 | 0.75 | MAPT (0.52) | ALDH1A1ALOX15ESR1ESR2CYP3A4 | |
| SCHEMBL21557850 | 0.75 | MAPT (0.52) | ALDH1A1ALOX15ESR1ESR2CYP3A4 | |
| SCHEMBL4326795 | 0.75 | MAPT (0.52) | ALDH1A1ALOX15ESR1ESR2CYP3A4 | |
| SCHEMBL198241 | 0.75 | MAPT (0.52) | ALDH1A1ALOX15ESR1ESR2CYP3A4 | |
| SCHEMBL153694 | 0.75 | MAPT (0.52) | ALDH1A1ALOX15ESR1ESR2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776322-A1 | METHOD FOR THE PREPARATION OF TAXOL AND ITS DERIVATIVES | PHARMACIA & UPJOHN S.p.A. (IT) | 1997-06-04 | — | — | EP | disclosed |
| WO-1997000870-A1 | METHOD FOR THE PREPARATION OF TAXOL AND ITS DERIVATIVES | PHARMACIA & UPJOHN S.P.A. (IT) | 1997-01-09 | — | — | WO | disclosed |
| EP-0079855-A1 | Alkylated hydroxyphenylthioalcanoic esters | CIBA-GEIGY AG (CH) | 1983-05-25 | — | — | EP | disclosed |