Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CHUK | O15111 | 2/20 | 0.34 |
| ▸ | INSR | P06213 | 2/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.34 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13982 | 0.93 | RIPK1 (0.42) | RIPK1SMYD3CCNCCDK8CHUK | |
| SCHEMBL12061506 | 0.92 | RIPK1 (0.39) | RIPK1SMYD3CCNCCDK8ATR | |
| SCHEMBL13865 | 0.92 | RIPK1 (0.40) | RIPK1SMYD3CHUKINSRMAPK8 | |
| SCHEMBL14364 | 0.91 | RIPK1 (0.40) | RIPK1NPC1RAB9ASMYD3SMN1; SMN2 | |
| SCHEMBL12061503 | 0.89 | MEN1 (0.38) | RIPK1CCNCCDK8CHUKINSR | |
| SCHEMBL14057 | 0.86 | RIPK1 (0.36) | RIPK1SMYD3CHUKINSRMAPK8 | |
| SCHEMBL12061498 | 0.85 | CHRNA7 (0.38) | TSHR | |
| SCHEMBL13764 | 0.84 | CHUK (0.37) | RIPK1CHUKINSRMAPK8CAMKK2 | |
| SCHEMBL12075844 | 0.84 | CHUK (0.45) | RIPK1CHUKINSRMAPK8CAMKK2 | |
| SCHEMBL12061490 | 0.82 | RIPK1 (0.39) | RIPK1CHUKINSRMAPK8CAMKK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011047319-A2 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2011-04-21 | — | — | WO | disclosed |