Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ACACB | O00763 | 6/20 | 0.35 |
| ▸ | CKS1B | P61024 | 1/20 | 0.35 |
| ▸ | SKP1 | P63208 | 1/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.35 |
| ▸ | ACACA | Q13085 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL140484 | 1.00 | DRD2 (0.37) | DRD2NAMPTKMT2AACACBCKS1B | |
| SCHEMBL147125 | 0.86 | DRD2 (0.40) | DRD2NAMPTKMT2AACACBCKS1B | |
| SCHEMBL146904 | 0.86 | DRD2 (0.40) | DRD2NAMPTKMT2AACACBCKS1B | |
| SCHEMBL141440 | 0.86 | DRD2 (0.40) | DRD2NAMPTKMT2AACACBCKS1B | |
| SCHEMBL142693 | 0.77 | DRD2 (0.41) | DRD2NAMPTKMT2AACACBCKS1B | |
| SCHEMBL141254 | 0.77 | DRD2 (0.41) | DRD2NAMPTKMT2AACACBCKS1B | |
| SCHEMBL144373 | 0.76 | DRD2 (0.39) | DRD2NAMPTKMT2AACACBCKS1B | |
| SCHEMBL142444 | 0.76 | DRD2 (0.39) | DRD2NAMPTKMT2AACACBCKS1B | |
| SCHEMBL144799 | 0.76 | DRD2 (0.35) | DRD2KMT2AACACBCKS1BSKP1 | |
| SCHEMBL142209 | 0.73 | DRD2 (0.39) | DRD2NAMPTKMT2AACACBCKS1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058989-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | ACHAOGEN, INC. (US) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058989-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | RECQL, BLVRB, NQO2 | DRD2 198/4885NAMPT 3516/4885KMT2A 4780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.