Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.42 |
| ▸ | MME | P08473 | 2/20 | 0.42 |
| ▸ | CPA1 | P15085 | 2/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | MASP2 | O00187 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | FURIN | P09958 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | KLK1 | P06870 | 1/20 | 0.37 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432218 | 0.93 | NAMPT (0.43) | ACEMMECPA1ACE2NAMPT | |
| SCHEMBL1432152 | 0.90 | KLKB1 (0.40) | NAMPTMASP2KLKB1CTSSCTSK | |
| SCHEMBL1432017 | 0.90 | MME (0.43) | ACEMMECPA1ACE2NAMPT | |
| SCHEMBL1432584 | 0.88 | MME (0.44) | ACEMMECPA1ACE2NAMPT | |
| SCHEMBL1432421 | 0.86 | KLKB1 (0.41) | MASP2KLKB1FURINKLK1 | |
| SCHEMBL1431636 | 0.86 | MME (0.43) | ACEMMECPA1ACE2NAMPT | |
| SCHEMBL3150292 | 0.86 | NAMPT (0.45) | NAMPTMASP2MEN1KMT2AKLKB1 | |
| SCHEMBL3150277 | 0.86 | NAMPT (0.45) | NAMPTMASP2MEN1KMT2AKLKB1 | |
| SCHEMBL3143640 | 0.86 | NAMPT (0.44) | ACEMMECPA1ACE2NAMPT | |
| SCHEMBL3143598 | 0.86 | NAMPT (0.44) | ACEMMECPA1ACE2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |